Document Detail

Histochemical localization of acid mannose 6-phosphatase activity in the newborn rat hepatocytes.
MedLine Citation:
PMID:  15693419     Owner:  NLM     Status:  MEDLINE    
The localization of acid mannose 6-phosphatase activity in newborn rat hepatocytes was demonstrated at the electron microscopic level by using a histochemical method based on the work of Robinson and Karnovsky. Reaction product was virtually restricted to the lysosomes. Most of them exhibited various grades of reactivity. Some were devoid of activity. Our observations suggested that this histochemical method could be used to differentiate distinct subpopulations of lysosomes on the basis of their acid mannose 6-phosphatase activity.
S A Kalamidas; O B Kotoulas; A C Hann
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Morphologie : bulletin de l'Association des anatomistes     Volume:  88     ISSN:  1286-0115     ISO Abbreviation:  Morphologie     Publication Date:  2004 Dec 
Date Detail:
Created Date:  2005-02-07     Completed Date:  2005-03-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9814314     Medline TA:  Morphologie     Country:  France    
Other Details:
Languages:  eng     Pagination:  176-8     Citation Subset:  IM    
Department of Anatomy, Histology and Embryology, Medical School, University of Ioannina, Ioannina 451 10, Greece.
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MeSH Terms
Animals, Newborn
Hepatocytes / enzymology*
Lysosomes / enzymology*
Phosphoric Monoester Hydrolases / metabolism*
Rats, Wistar
Reg. No./Substance:
EC 3.1.3.-/Phosphoric Monoester Hydrolases; EC 3.1.3.-/mannose-6-phosphatase

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