Document Detail

Histochemical demonstration of gastrointestinal mucins in ovarian mucinous cystadenoma.
MedLine Citation:
PMID:  1373263     Owner:  NLM     Status:  MEDLINE    
Forty-one specimens of mucinous cystadenoma (MCA) of the ovary and 13 specimens of normal uterine endocervix were investigated histochemically using alcian blue pH 2.5-PAS, high iron diamine-alcian blue pH 2.5, galactose oxidase-Schiff reaction (GOS, for detection of gastric surface mucous cell mucins), paradoxical Concanavalin A staining (PCS, for detection of gastric gland cell mucins) and periodic acid-sodium borohydride-potassium hydroxide-PAS (PA-SB-PH-PAS) reaction (for detection of mucins of the large intestine). In addition, Grimelius staining was carried out to explore the distribution of endocrine cells. The MCAs contained abundant neutral mucins but a little acid mucins, whereas sulfomucins predominated in normal endocervices. Among the MCAs, 30, 26, 2 and 9 had tumor cells positive for GOS, PCS, PA-SB-PH-PAS and Grimelius stain, respectively. These results indicate that MCAs frequently contain tumor cells of the gastrointestinal type and endocrine cell type. Endocervical epithelia, on the other hand, lack reactivity for PCS, PA-SB-PH-PAS and Grimelius stain, although in 8 of the present specimens, the lining cells showed weak GOS reactivity.
T Shiozawa; Y Tsukahara; K Ishii; H Ota; J Nakayama; T Katsuyama
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Acta pathologica japonica     Volume:  42     ISSN:  0001-6632     ISO Abbreviation:  Acta Pathol. Jpn.     Publication Date:  1992 Feb 
Date Detail:
Created Date:  1992-05-14     Completed Date:  1992-05-14     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0372637     Medline TA:  Acta Pathol Jpn     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  104-10     Citation Subset:  IM    
Department of Gynecology and Obstetrics, Shinshu University School of Medicine, Matsumoto, Japan.
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MeSH Terms
Aged, 80 and over
Cystadenoma / chemistry*,  pathology
Gastric Mucins / analysis*
Middle Aged
Ovarian Neoplasms / chemistry*,  pathology
Reg. No./Substance:
0/Gastric Mucins

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