| Histochemical characterization of the lead intranuclear inclusion bodies. | |
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MedLine Citation:
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PMID: 11051614 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A battery of histological and histochemical techniques was applied on the lead intranuclear bodies that have resuted in the kidneys of adult Wistar male rats receiving lead acetate in their diet to determine their nature. The intranuclear inclusion bodies have stained strongly with xanthene, anthraquinone, and trisulfonated basophilic dyes and weakly with dyes containing both positive and negative radicals, and they have responded negatively to acidophilic cationic dyes. They have also reacted positively to proteins and lead stains, but weakly to lipid stains, and negatively to Feulgen and methyl green pyronin techniques. The intranuclear bodies proved to be lead lipoprotein complexes containing sulfyhydryl groups and are basic in nature with orthochromatic, eosinophilic, argyrophilic, osmophilic, fuchsinophilic, and sudanophilic characteristics. |
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Authors:
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B M Jarrar; Z N Mahmoud |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Biological trace element research Volume: 75 ISSN: 0163-4984 ISO Abbreviation: Biol Trace Elem Res Publication Date: 2000 |
Date Detail:
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Created Date: 2000-11-16 Completed Date: 2000-11-16 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7911509 Medline TA: Biol Trace Elem Res Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 245-51 Citation Subset: IM |
Affiliation:
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Department of Zoology, College of Science, King Saud University, Riyadh, Saudi Arabia. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cell Nucleus Structures / chemistry* Coloring Agents DNA / chemistry, genetics Histocytochemistry Inclusion Bodies / chemistry*, pathology Kidney / pathology Kidney Tubules, Proximal / pathology Lead / chemistry* Male RNA / chemistry, genetics Rats Rats, Wistar |
| Chemical | |
Reg. No./Substance:
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0/Coloring Agents; 63231-63-0/RNA; 7439-92-1/Lead; 9007-49-2/DNA |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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