Document Detail

Histiocytosis X with unusual skin symptoms.
MedLine Citation:
PMID:  6172939     Owner:  NLM     Status:  MEDLINE    
A 4-year-old boy with skin symptoms resembling verruca plana juvenile was observed. The light- and electron-microscopic picture showed the typical features of histiocytosis X (Letterer-Siwe syndrome). Beside the skin manifestations some less dense areas in the skull bones were found by X-ray examination. Vinblastine and prednisolone treatment for one year resulted in complete remission.
K Nagy-Vezekényi; A Makai; I Ambró; E Nagy
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta dermato-venereologica     Volume:  61     ISSN:  0001-5555     ISO Abbreviation:  Acta Derm. Venereol.     Publication Date:  1981  
Date Detail:
Created Date:  1982-03-13     Completed Date:  1982-03-13     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0370310     Medline TA:  Acta Derm Venereol     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  447-51     Citation Subset:  IM    
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MeSH Terms
Child, Preschool
Histiocytes / ultrastructure
Histiocytosis, Langerhans-Cell / complications*,  drug therapy
Organoids / ultrastructure
Prednisolone / therapeutic use
Skin / pathology
Skin Diseases / etiology*,  pathology
Vinblastine / therapeutic use
Reg. No./Substance:
50-24-8/Prednisolone; 865-21-4/Vinblastine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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