Document Detail

Histiocytosis X involving the thyroid and hypothalamus.
MedLine Citation:
PMID:  1924059     Owner:  NLM     Status:  MEDLINE    
A case of histiocytosis X involving the thyroid and hypothalamus is reported. A 16 year old female presented with amenorrhoea and diabetes insipidus. She subsequently developed a painful goitre with biochemical hypothyroidism, and stridor. The stridor and goitre responded to cyclophosphamide. Previous publications on the use of cytotoxics in histiocytosis X involving the thyroid are reviewed. We describe for the first time both the ultrasound appearances of the thyroid in this condition and the use of serial volumetric measurements to monitor therapy.
P Gaines; J C Chan; C S Cockram
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Postgraduate medical journal     Volume:  67     ISSN:  0032-5473     ISO Abbreviation:  Postgrad Med J     Publication Date:  1991 Jul 
Date Detail:
Created Date:  1991-11-21     Completed Date:  1991-11-21     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0234135     Medline TA:  Postgrad Med J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  680-2     Citation Subset:  IM    
Department of Radiology, Prince of Wales Hospital, Shatin, New Territories, Hong Kong.
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MeSH Terms
Cyclophosphamide / therapeutic use
Goiter / etiology
Histiocytosis, Langerhans-Cell / complications*,  diagnosis,  drug therapy
Hypothalamic Diseases / complications*
Respiratory Sounds / etiology*
Thyroid Diseases / complications*
Reg. No./Substance:

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