Document Detail


Histiocytic lymphoma of the ileocecal region after chemotherapy for multiple myeloma.
MedLine Citation:
PMID:  369675     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Histiocytic lymphoma of the ileocecal region developed in a patient with multiple myeloma following successful long-term alkylating agent therapy. Five and one-half years after the diagnosis of myeloma, while in remission on cyclophosphamide therapy, the patient experienced severe abdominal right lower quadrant pain due to a large cecal lymphoma. A right hemicolectomy was performed with relief of symptoms. However, 9 months later, while still asymptomatic, routine physical examination revealed a recurrent right lower quadrant tumor. Radiation therapy decreased the size of the mass, but five months later partial small bowel obstruction occurred because of recurrent lymphomatous infiltration. The patient died 7 years after the diagnosis of myeloma with extensive abdominal lymphoma. There was no evidence of recurrent myeloma after the initial remission on cyclophosphamide therapy. This patient adds to the growing literature of a second malignancy occurring after prolonged successful chemotherapy of a primary neoplasm.
Authors:
S B Kapadia
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Cancer     Volume:  43     ISSN:  0008-543X     ISO Abbreviation:  Cancer     Publication Date:  1979 Feb 
Date Detail:
Created Date:  1979-05-24     Completed Date:  1979-05-24     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0374236     Medline TA:  Cancer     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  435-9     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Cecal Neoplasms / chemically induced*,  pathology
Cyclophosphamide / adverse effects*
Humans
Ileocecal Valve
Lymphoma, Large B-Cell, Diffuse / chemically induced*,  pathology
Male
Middle Aged
Multiple Myeloma / drug therapy*
Neoplasms, Multiple Primary / chemically induced*,  pathology
Remission, Spontaneous
Time Factors
Chemical
Reg. No./Substance:
50-18-0/Cyclophosphamide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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