| Histamine and the stomach: chemical histamine assays. | |
| | |
MedLine Citation:
|
PMID: 1828307 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Histamine assays in gastroduodenal tissues and body fluids are not an absolute objective of scientific interest but are related to the role of histamine in health and disease. Hence, the reliability of histamine assays has to be assessed in relation to this aim. Sensitivity and specificity of the chemical histamine assays are similar in tissues and body fluids. The modern developments in a fluorometric-fluoroenzymatic assay guarantee the highest sensitivity and specificity, especially by tests that monitor specificity in each single run of histamine determinations. Precision and accuracy of histamine measurement were especially investigated for the fluorometric assay. They included tests on the coefficient of variation over the whole concentration range, long-term precision with double-sample standard control charts, comparison of several methods for histamine assay including bioassay, and long-term accuracy with the use of Cusum charts. Finally, appropriate sample preparation, sample-taking, relevant body fluids and tissues, and the right time for sample-taking were evaluated in extended methodologic studies. Histamine assays are not just methods for a normal routine laboratory. Extended knowledge about histamine release and metabolism will be necessary to analyse data in this particular field with reasonable validity. |
| | |
Authors:
|
W Lorenz; K Thon; H Stöltzing; E Neugebauer; R Lindlar; J Sattler; D Weber |
Related Documents
:
|
8070087 - Quantification of skeletal alkaline phosphatase in osteoporotic serum by wheat germ agg... 22281317 - Comparison of the metabolic profiles of noncoagulating and coagulating bovine milk. 17032127 - Uncertainty calculation for calibrators and controls of laboratory diagnostic assays. 709837 - Relative merits of two electrophoretic and two column-chromatographic kets for determin... 14570177 - A microchip electrophoresis device with integrated electrochemical detection: a direct ... 10225407 - Acanthamoeba keratitis: increased sensitivity of the detection of parasites by modified... |
Publication Detail:
|
Type: Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Scandinavian journal of gastroenterology. Supplement Volume: 180 ISSN: 0085-5928 ISO Abbreviation: Scand. J. Gastroenterol. Suppl. Publication Date: 1991 |
Date Detail:
|
Created Date: 1991-07-11 Completed Date: 1991-07-11 Revised Date: 2008-02-13 |
Medline Journal Info:
|
Nlm Unique ID: 0437034 Medline TA: Scand J Gastroenterol Suppl Country: NORWAY |
Other Details:
|
Languages: eng Pagination: 9-25 Citation Subset: IM |
Affiliation:
|
Institute of Theoretical Surgery, University of Marburg/Lahn, Germany. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Biological Assay Chromatography, High Pressure Liquid / standards Decision Trees Fluorometry / standards Gas Chromatography-Mass Spectrometry / standards Gastric Mucosa / chemistry* Histamine / analysis* Humans Intestinal Mucosa / chemistry* Meta-Analysis as Topic Peptic Ulcer / metabolism* Radioimmunoassay / standards Sensitivity and Specificity |
| Chemical | |
Reg. No./Substance:
|
51-45-6/Histamine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Diurnal variation of plasma atrial natriuretic peptide in normals and patients with enuresis nocturn...
Next Document: Musculoskeletal syndromes associated with acne.