Document Detail


Histamine in cardiac sympathetic ganglia: a novel neurotransmitter?
MedLine Citation:
PMID:  16507745     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Although ganglia in the heart are well known to be cholinergic, many other neurotransmitters and neuropeptides also influence (and are produced in) cardiac neurons, including adrenergic and purinergic compounds. Recently, histamine was suggested as a possible neurotransmitter in cardiac tissue. Although histamine does elicit many effects in the heart, does it stand up to rigorous scrutiny and fulfill certain criteria that are used to define neurotransmitters?
Authors:
Ryan M Fryer; Glenn A Reinhart; Timothy A Esbenshade
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Molecular interventions     Volume:  6     ISSN:  1534-0384     ISO Abbreviation:  Mol. Interv.     Publication Date:  2006 Feb 
Date Detail:
Created Date:  2006-03-01     Completed Date:  2007-06-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101093789     Medline TA:  Mol Interv     Country:  United States    
Other Details:
Languages:  eng     Pagination:  14-9, 2     Citation Subset:  IM    
Affiliation:
Department of Integrative Pharmacology, Abbott Laboratories, Abott Park, IL 60064-6119, USA. ryan.fryer@abbott.com
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MeSH Terms
Descriptor/Qualifier:
Ganglia, Sympathetic / metabolism*
Histamine / metabolism*
Humans
Myocardium / metabolism*
Neurotransmitter Agents / metabolism*
Chemical
Reg. No./Substance:
0/Neurotransmitter Agents; 51-45-6/Histamine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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