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Histamine H3 Receptor Function and Ligands: Recent Developments.
MedLine Citation:
PMID:  22931528     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Histamine H3 receptors are found mostly in central nervous system involved in regulation of release of various neurotransmitters in brain. They have been implicated in diverse potential therapeutic applications such as sleep-wake disorders, attention-deficient hyperactivity disorder, epilepsy, cognitive impairment and obesity. This review is an attempt to elucidate the function of H3 receptors and their role in various CNS disorders. Also, it is aimed at collating the information on efforts of various medicinal chemists to synthesize the H3 receptor agonists and antagonists in single article.
Authors:
Mahaveer Singh; Hemant R Jadhav
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-8-27
Journal Detail:
Title:  Mini reviews in medicinal chemistry     Volume:  -     ISSN:  1875-5607     ISO Abbreviation:  Mini Rev Med Chem     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-8-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101094212     Medline TA:  Mini Rev Med Chem     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Pharmacy, Birla Institute of Technology and Sciences Pilani, Pilani Campus, Vidya Vihar - 333031, Rajasthan, India. hemantrj@gmail.com, hemantrj@bits-pilani.ac.in.
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