Document Detail


Hispidacine, an unusual 8,4'-oxyneolignan-alkaloid with vasorelaxant activity, and hispiloscine, an antiproliferative phenanthroindolizidine alkaloid, from Ficus hispida Linn.
MedLine Citation:
PMID:  25468714     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Hispidacine, an 8,4'-oxyneolignan featuring incorporation of an unusual 2-hydroxyethylamine moiety at C-7, and hispiloscine, a phenanthroindolizidine alkaloid, were isolated from the stem-bark and leaves of the Malaysian Ficus hispida Linn. Their structures were established by spectroscopic analysis. Hispidacine induced a moderate vasorelaxant activity in rat isolated aorta, while hispiloscine showed appreciable antiproliferative activities against MDA-MB-231, MCF-7, A549, HCT-116 and MRC-5 cell lines.
Authors:
Veronica Alicia Yap; Bi-Juin Long; Kang-Nee Ting; Sandy Hwei-San Loh; Kien-Thai Yong; Yun-Yee Low; Toh-Seok Kam; Kuan-Hon Lim
Related Documents :
25446364 - Species differences in androgen receptor expression in the medial preoptic and anterior...
25243914 - Spermicidal and contraceptive potential of desgalactotigonin: a prospective alternative...
21647384 - Asthma pregnancy alters postnatal development of chromaffin cells in the rat adrenal me...
25371794 - β-d-glucan assay in diagnosis and monitoring the systemic candidiasis in a rat model.
1124984 - Nervous system degeneration produced by the industrial solvent methyl n-butyl ketone.
6278834 - Investigations on the occurrence of cytidine 3',5' monophosphate (ccmp) in tissues.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-11-19
Journal Detail:
Title:  Phytochemistry     Volume:  109C     ISSN:  1873-3700     ISO Abbreviation:  Phytochemistry     Publication Date:  2014 Nov 
Date Detail:
Created Date:  2014-12-3     Completed Date:  -     Revised Date:  2014-12-4    
Medline Journal Info:
Nlm Unique ID:  0151434     Medline TA:  Phytochemistry     Country:  -    
Other Details:
Languages:  ENG     Pagination:  96-102     Citation Subset:  -    
Copyright Information:
Copyright © 2014 Elsevier Ltd. All rights reserved.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Ryecyanatines A and B and ryecarbonitrilines A and B, substituted cyanatophenol, cyanatobenzo[1,3]di...
Next Document:  Clinical impact of herpesvirus entry mediator expression in human hepatocellular carcinoma.