Document Detail


Highly sensitive and selective dopamine biosensor based on 3,4,9,10-perylene tetracarboxylic acid functionalized graphene sheets/multi-wall carbon nanotubes/ionic liquid composite film modified electrode.
MedLine Citation:
PMID:  22951031     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
A sensitive and selective electrochemical sensor for determination of dopamine (DA) was fabricated based on 3,4,9,10-perylene tetracarboxylic acid functionalized graphene sheets, multi-wall carbon nanotubes and ionic liquid modified glass carbon electrode and the properties of modified electrode were characterized by scanning electron microscopy, transmission electron microscope and electrochemical impedance spectroscopy. The modified electrode showed excellent electrocatalytic activity toward the oxidation of DA. Meanwhile, a possible reaction mechanism related to the oxidation of DA was proposed. The differential pulse voltammetry was used for the determination of DA in the presence of 500μM ascorbic acid and 330μM uric acid under the optimum conditions and a good linear relationship between peak current and the concentration of DA was obtained in the concentration range from 0.03μM to 3.82mM with a detection limit of 1.2×10(-9)M (S/N=3). Moreover, the proposed method was successfully applied to determine DA in real sample and satisfactory results were obtained. The results showed that the modified electrode exhibits an excellent catalytic activity, good sensitivity, reproducibility and long-term stability.
Authors:
Xiuli Niu; Wu Yang; Hao Guo; Jie Ren; Jinzhang Gao
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-8-23
Journal Detail:
Title:  Biosensors & bioelectronics     Volume:  -     ISSN:  1873-4235     ISO Abbreviation:  Biosens Bioelectron     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-9-6     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9001289     Medline TA:  Biosens Bioelectron     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012. Published by Elsevier B.V.
Affiliation:
College of Chemistry and Chemical Engineering, Key Lab of Bioelectrochemistry and Environmental Analysis of Gansu Province, Northwest Normal University, Lanzhou 730070, PR China.
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