Document Detail


Highly enantioselective gamma-amination of alpha,beta-unsaturated acycl chlorides with azodicarboxylates. Efficient synthesis of chiral gamma-amino acid derivatives.
MedLine Citation:
PMID:  21902208     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The cinchona alkaloids-catalyzed γ-amination of α,β-unsaturated acyl chlorides with azodicarboxylates was developed to give the corresponding dihydropyridazinones in good yields with high enantioselectivities. Reductive ring-opening of the dihydropyridazinones afforded series of cyclic and acyclic γ-amino acid derivatives in good yields with high enantiopurity.
Authors:
Li-Tao Shen; Li-Hui Sun; Song Ye
Related Documents :
3017308 - A re-evaluation of evidence attributing the difference in cleavage rates of restriction...
20717778 - The oral microbiota: general overview, taxonomy, and nucleic acid techniques.
19175328 - Solid-phase synthesis of oligonucleotide conjugates useful for delivery and targeting o...
15828758 - Selective determination of the doxorubicin content of individual acidic organelles in i...
67738 - Histochemical methods for proteins in tissues submitted to decalcification. a histophot...
18830468 - A persistent p,n-heterocyclic carbene.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-9-8
Journal Detail:
Title:  Journal of the American Chemical Society     Volume:  -     ISSN:  1520-5126     ISO Abbreviation:  -     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-9-9     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7503056     Medline TA:  J Am Chem Soc     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Polarization Closure in PbZr<sub>(0.42)</sub>Ti<sub>(0.58)</sub>O<sub>3</sub> Nanodots.
Next Document:  Self Assembled Liquid Crystal Polymers on Photo-Irradiated Alignment Surfaces for Tailoring Response...