Document Detail


Highly enantioselective deracemization of linear and vaulted biaryl ligands.
MedLine Citation:
PMID:  12762659     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
[reaction: see text] A copper-mediated deracemization of the vaulted biaryl ligands VANOL and VAPOL can be readily achieved in the presence of (-)-spartiene. The optimal procedure involves the in situ generation of copper(II) and leads to the reproducible formation of (S)-VANOL and (S)-VAPOL in greater than 99% ee from the racemates. This method is superior to existing procedures for BINOL (92% ee).
Authors:
Yu Zhang; Siu-Man Yeung; Hongqiao Wu; Douglas P Heller; Chunrui Wu; William D Wulff
Related Documents :
10400859 - Self-reported allergic reactions to peanut on commercial airliners.
24641899 - Restriction of food intake prevents postinfarction heart failure accompanying enhanced ...
25398749 - Portion size and obesity.
22176299 - Growth of pseudomonas fluorescens in modified atmosphere packaged tofu.
2760579 - Induction of the acrosome reaction in goat spermatozoa in simple physiological salt sol...
16852939 - Zno nanobelt arrays grown directly from and on zinc substrates: synthesis, characteriza...
213019 - New medium for rapid screening and enumeration of clostridium perfringens in foods.
18441429 - Effect of protein on biohydrogen production from starch of food waste.
15775679 - Following the rules: why small groups of tamarins do not reconcile conflicts.
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Organic letters     Volume:  5     ISSN:  1523-7060     ISO Abbreviation:  Org. Lett.     Publication Date:  2003 May 
Date Detail:
Created Date:  2003-05-23     Completed Date:  2003-09-08     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  100890393     Medline TA:  Org Lett     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1813-6     Citation Subset:  IM    
Affiliation:
Department of Chemistry, Michigan State University, East Lansing, Michigan 48824, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Bicyclo Compounds / chemistry*
Copper / chemistry
Ligands*
Models, Molecular
Sparteine / chemistry
Stereoisomerism
Ultrasonics
Grant Support
ID/Acronym/Agency:
GM 63019/GM/NIGMS NIH HHS
Chemical
Reg. No./Substance:
0/Bicyclo Compounds; 0/Ligands; 7440-50-8/Copper; 90-39-1/Sparteine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Catalytic asymmetric rearrangement of allylic N-aryl trifluoroacetimidates. A useful method for tran...
Next Document:  Preparation and characterization of alpha,alpha'-bisdiarylamino-capped oligothiophenes.