| Highly sensitive and selective dynamic light-scattering assay for TNT detection using p-ATP attached gold nanoparticle. | |
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MedLine Citation:
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PMID: 21077646 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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TNT is one of the most commonly used nitro aromatic explosives for landmines of military and terrorist activities. As a result, there is an urgent need for rapid and reliable methods for the detection of trace amount of TNT for screenings in airport, analysis of forensic samples, and environmental analysis. Driven by the need to detect trace amounts of TNT from environmental samples, this article demonstrates a label-free, highly selective, and ultrasensitive para-aminothiophenol (p-ATP) modified gold nanoparticle based dynamic light scattering (DLS) probe for TNT recognition in 100 pico molar (pM) level from ethanol:acetonitile mixture solution. Because of the formation of strong π-donor-acceptor interaction between TNT and p-ATP, para-aminothiophenol attached gold nanoparticles undergo aggregation in the presence of TNT, which changes the DLS intensity tremendously. A detailed mechanism for significant DLS intensity change has been discussed. Our experimental results show that TNT can be detected quickly and accurately without any dye tagging in 100 pM level with excellent discrimination against other nitro compounds. |
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Authors:
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Samuel S R Dasary; Dulal Senapati; Anant Kumar Singh; Yerramilli Anjaneyulu; Hongtao Yu; Paresh Chandra Ray |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S. Date: 2010-11-15 |
Journal Detail:
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Title: ACS applied materials & interfaces Volume: 2 ISSN: 1944-8244 ISO Abbreviation: ACS Appl Mater Interfaces Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-12-23 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101504991 Medline TA: ACS Appl Mater Interfaces Country: United States |
Other Details:
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Languages: eng Pagination: 3455-60 Citation Subset: IM |
Affiliation:
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Department of Chemistry, Jackson State University, Jackson, Mississippi 39217, United States. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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