Document Detail

Higher success rate by intracytoplasmic sperm injection than by subzonal insemination. Report of a second series of 300 consecutive treatment cycles.
MedLine Citation:
PMID:  8408486     Owner:  NLM     Status:  MEDLINE    
Subzonal insemination (SUZI) and intracytoplasmic sperm injection (ICSI) were carried out in 300 treatment cycles in couples unable to be helped by conventional in-vitro fertilization treatment. More oocytes were damaged by ICSI (13.5%) than by SUZI (7.1%). The normal fertilization rate was substantially higher after ICSI (51.0%) than after SUZI (14.3%) and was related to the semen characteristics. The cleavage rate was similar for both procedures (77%). After 217 embryo transfers (72.3% of the treatment cycles) 66 pregnancies were established, i.e. pregnancy rates of 22.0% per started cycle and 30.4% per embryo transfer. So far, pregnancy loss has occurred in 27.3% of the pregnancies, nine healthy children have been born after eight deliveries and 41 clinical pregnancies are progressing uneventfully. Chorionic villus sampling or amniocentesis have been performed in 35 pregnancies and 39 normal fetal karyotypes have been obtained after cytogenetic analysis.
A C Van Steirteghem; J Liu; H Joris; Z Nagy; C Janssenswillen; H Tournaye; M P Derde; E Van Assche; P Devroey
Related Documents :
11104266 - Can relative spermatozoal galactosyltransferase activity be predictive of dairy bull fe...
15157796 - Restoration of fertility in vasectomized men using percutaneous vasal or epididymal spe...
16009166 - In vitro fertilization-intracytoplasmic sperm injection success rates with cryopreserve...
15611566 - A different female partner does not affect the success of second vasectomy reversal.
11527466 - Molecular phylogeny of gobioid fishes (perciformes: gobioidei) based on mitochondrial 1...
24220686 - Conditions causing disability and current pregnancy among us women with chronic physica...
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Human reproduction (Oxford, England)     Volume:  8     ISSN:  0268-1161     ISO Abbreviation:  Hum. Reprod.     Publication Date:  1993 Jul 
Date Detail:
Created Date:  1993-10-28     Completed Date:  1993-10-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8701199     Medline TA:  Hum Reprod     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1055-60     Citation Subset:  IM    
Centre for Reproductive Medicine, Academisch Ziekenhuis VUB, Brussels, Belgium.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Fertilization in Vitro / methods*
Infertility, Male*
Insemination, Artificial*
Pregnancy Outcome
Zona Pellucida

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Chromosome anomalies in human oocytes in relation to age.
Next Document:  High fertilization and implantation rates after intracytoplasmic sperm injection.