| Higher success rate by intracytoplasmic sperm injection than by subzonal insemination. Report of a second series of 300 consecutive treatment cycles. | |
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MedLine Citation:
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PMID: 8408486 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Subzonal insemination (SUZI) and intracytoplasmic sperm injection (ICSI) were carried out in 300 treatment cycles in couples unable to be helped by conventional in-vitro fertilization treatment. More oocytes were damaged by ICSI (13.5%) than by SUZI (7.1%). The normal fertilization rate was substantially higher after ICSI (51.0%) than after SUZI (14.3%) and was related to the semen characteristics. The cleavage rate was similar for both procedures (77%). After 217 embryo transfers (72.3% of the treatment cycles) 66 pregnancies were established, i.e. pregnancy rates of 22.0% per started cycle and 30.4% per embryo transfer. So far, pregnancy loss has occurred in 27.3% of the pregnancies, nine healthy children have been born after eight deliveries and 41 clinical pregnancies are progressing uneventfully. Chorionic villus sampling or amniocentesis have been performed in 35 pregnancies and 39 normal fetal karyotypes have been obtained after cytogenetic analysis. |
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Authors:
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A C Van Steirteghem; J Liu; H Joris; Z Nagy; C Janssenswillen; H Tournaye; M P Derde; E Van Assche; P Devroey |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Human reproduction (Oxford, England) Volume: 8 ISSN: 0268-1161 ISO Abbreviation: Hum. Reprod. Publication Date: 1993 Jul |
Date Detail:
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Created Date: 1993-10-28 Completed Date: 1993-10-28 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8701199 Medline TA: Hum Reprod Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 1055-60 Citation Subset: IM |
Affiliation:
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Centre for Reproductive Medicine, Academisch Ziekenhuis VUB, Brussels, Belgium. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Female Fertilization in Vitro / methods* Humans Infertility, Male* Insemination, Artificial* Male Microinjections Pregnancy Pregnancy Outcome Zona Pellucida |
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