Document Detail

Higher risk of preeclampsia in the polycystic ovary syndrome. A case control study.
MedLine Citation:
PMID:  9481555     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To determine whether the risk of pregnancy-induced hypertensive disorders (PIHD) is higher in patients with the polycystic ovary syndrome (PCOS) than in non-PCOS controls, matched for age and parity. STUDY DESIGN: Retrospective analysis of eighty-one patients with PCOS, consecutively becoming pregnant during a seven-year period. Each PCOS-patient was matched for age and parity with one control patient. Chi-squared, Mann-Whitney or Fisher's exact-tests were used for statistical analysis. RESULTS: Overall incidence of PIHD was similar in both study groups. However, incidence of preeclampsia was significantly higher in patients with PCOS than in controls (P = 0.02). This higher incidence can not be explained by body mass index, endocrine profile before pregnancy, induction of ovulation or treatment regimens. CONCLUSIONS: PCOS-patients are at a significantly higher risk for preeclampsia than non-PCOS controls.
M J de Vries; G A Dekker; J Schoemaker
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of obstetrics, gynecology, and reproductive biology     Volume:  76     ISSN:  0301-2115     ISO Abbreviation:  Eur. J. Obstet. Gynecol. Reprod. Biol.     Publication Date:  1998 Jan 
Date Detail:
Created Date:  1998-04-01     Completed Date:  1998-04-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0375672     Medline TA:  Eur J Obstet Gynecol Reprod Biol     Country:  IRELAND    
Other Details:
Languages:  eng     Pagination:  91-5     Citation Subset:  IM    
Department of Obstetrics and Gynaecology, Free University Hospital of Amsterdam, The Netherlands.
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MeSH Terms
Body Mass Index
Case-Control Studies
Follicle Stimulating Hormone / blood
Luteinizing Hormone / blood
Ovulation Induction
Polycystic Ovary Syndrome / complications*,  physiopathology
Pre-Eclampsia / epidemiology,  etiology*,  physiopathology
Prolactin / blood
Retrospective Studies
Risk Factors
Reg. No./Substance:
9002-62-4/Prolactin; 9002-67-9/Luteinizing Hormone; 9002-68-0/Follicle Stimulating Hormone

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