Document Detail


Higher pregnancy rates following treatment of cervical factor with intrauterine insemination without superovulation versus intercourse: the importance of a well-timed postcoital test for infertility.
MedLine Citation:
PMID:  8554435     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A randomized study comparing the efficacy of timed intrauterine insemination (IUI) without hyperstimulation to sexual intercourse was performed in women with cervical factor infertility. Among the strict requirements for inclusion in the study were a normal semen analysis in the male partner, as well as the failure to demonstrate any sperm with progressive forward motion in a postcoital test performed 8-12 h after intercourse at the time of a mature follicle. All other infertility factors were negative. The data demonstrated a statistically significant fecundity rate at 1 month when IUI was compared to intercourse (21.2 vs. 3.9%). These data suggest that carefully timed IUI in nonhyperstimulated cycles is an effective treatment for cervical factor infertility.
Authors:
J H Check; P Spirito
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Archives of andrology     Volume:  35     ISSN:  0148-5016     ISO Abbreviation:  Arch. Androl.     Publication Date:    1995 Jul-Aug
Date Detail:
Created Date:  1996-02-20     Completed Date:  1996-02-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7806755     Medline TA:  Arch Androl     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  71-7     Citation Subset:  IM    
Affiliation:
University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden, USA.
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MeSH Terms
Descriptor/Qualifier:
Bromocriptine / therapeutic use
Clomiphene / therapeutic use
Coitus*
Female
Fertility Agents, Female / therapeutic use
Humans
Infertility, Female* / diagnosis*,  etiology
Insemination, Artificial, Homologous*
Male
Menotropins / therapeutic use
Pregnancy
Pregnancy Outcome
Semen
Superovulation*
Uterine Cervical Diseases*
Uterus
Chemical
Reg. No./Substance:
0/Fertility Agents, Female; 25614-03-3/Bromocriptine; 61489-71-2/Menotropins; 911-45-5/Clomiphene

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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