Document Detail


Higher calcaneal bone mineral density in men with metabolic syndrome in a Chinese population.
MedLine Citation:
PMID:  23320779     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The metabolic syndrome (MS) is characterized by abdominal obesity, impaired glucose tolerance, hypertension and dyslipidemia. Abdominal adiposity and insulin resistance appear to be at the core of the pathophysiology of MS and its individual components (1) As we known obesity or high body mass index (BMI) were associated with high bone mass and protected against excessive aging-related bone loss(2,3) Conversely, insulin resistance has a strong association with low grade inflammation which results in increased bone resorption(4) Similarly, MS has both of the two conflicting core factors of BMD, obesity protecting bone mass but insulin resistance activing bone resorption. As a result, we conducted a cross sectional study to examine the relationship between MS and bone mineral density (BMD). © 2013 Ruijin Hospital, Shanghai Jiaotong University School of Medicine and Wiley Publishing Asia Pty Ltd.
Authors:
Nan Zhao; Xulei Tang; Donghu Zhen; Huihui Liu
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Publication Detail:
Type:  LETTER     Date:  2013-1-16
Journal Detail:
Title:  Journal of diabetes     Volume:  -     ISSN:  1753-0407     ISO Abbreviation:  J Diabetes     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101504326     Medline TA:  J Diabetes     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2013 Ruijin Hospital, Shanghai Jiaotong University School of Medicine and Wiley Publishing Asia Pty Ltd.
Affiliation:
Department of Endocrinology, The First Hospital of Lanzhou University, Donggang West Road, Lanzhou, Gansu, China, 730000.
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