Document Detail


High-voltage irradiation and combination chemotherapy for malignant pheochromocytoma.
MedLine Citation:
PMID:  3135110     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 29-year-old man with metastatic extraadrenal pheochromocytoma developed paraplegia which reversed completely after megavoltage irradiation of the dorsolumbar spine. Later, treated with cyclophosphamide, vincristine, and dacarbazine, he had a temporary decrease in plasma norepinephrine concentration, a partial recalcification of bone lesions, and a decrease in the need for antihypertensive treatment for 12 months. Irradiation and combination chemotherapy should be evaluated further in the management of malignant pheochromocytoma.
Authors:
M Z Siddiqui; F E Von Eyben; G Spanos
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Cancer     Volume:  62     ISSN:  0008-543X     ISO Abbreviation:  Cancer     Publication Date:  1988 Aug 
Date Detail:
Created Date:  1988-09-01     Completed Date:  1988-09-01     Revised Date:  2006-04-24    
Medline Journal Info:
Nlm Unique ID:  0374236     Medline TA:  Cancer     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  686-90     Citation Subset:  AIM; IM    
Affiliation:
Department of Oncology, Tawam Hospital, Al Ain, Abu Dhabi, United Arab Emirates.
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MeSH Terms
Descriptor/Qualifier:
Adult
Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
Blood Pressure / drug effects
Bone Neoplasms / drug therapy,  radiotherapy,  secondary*
Combined Modality Therapy
Heart Rate / drug effects
Humans
Male
Norepinephrine / blood
Paraplegia / etiology
Pheochromocytoma / drug therapy,  radiotherapy,  secondary*
Radiotherapy, High-Energy*
Chemical
Reg. No./Substance:
51-41-2/Norepinephrine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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