Document Detail

High triglyceride level is associated with severe coronary artery disease in hypertensive subjects.
MedLine Citation:
PMID:  18365898     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The contribution of triglycerides (TG) to the extent of coronary artery disease (CAD) in hypertensive patients remained unclear. METHODS: Consecutive 821 (aged 64.5+/-11.5 years, 482 males) hypertensive patients undergoing coronary angiography were included. The relationship of TG levels (<150 vs. > or =150 mg/dl) to the extent of CAD in all patients was examined by multiple logistic regression, adjusting for other CAD risk factors. In the lipid group, low levels of HDL were also adjusted. RESULTS: Higher levels of TG were found in subjects with severe CAD compared to those with no or minimal CAD. The adjusted odds ratios for high levels of TG in the severe CAD subgroup versus the no or minimal CAD subgroup were 5.20 (95% CI, 3.13 to 8.63) in all patients and 7.51 (95% CI, 3.19 to 17.65) in the lipid group. CONCLUSIONS: High levels of TG are strong clinical markers of greater extent of CAD in hypertensive subjects undergoing coronary angiography. The results may have clinical relevance for physicians in therapeutic decision making.
Chun-Yen Chen; Chii-Min Hwu; Ming-Wei Lin; Cheng-Ho Tsai; Hung-I Yeh
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Scandinavian cardiovascular journal : SCJ     Volume:  42     ISSN:  1401-7431     ISO Abbreviation:  Scand. Cardiovasc. J.     Publication Date:  2008 Apr 
Date Detail:
Created Date:  2008-03-27     Completed Date:  2008-08-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9708377     Medline TA:  Scand Cardiovasc J     Country:  England    
Other Details:
Languages:  eng     Pagination:  146-52     Citation Subset:  IM    
Cardiovascular Division, Department of Internal Medicine, Mackay Memorial Hospital, Taipei, Taiwan.
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MeSH Terms
Coronary Angiography
Coronary Artery Disease / blood*,  epidemiology,  radiography
Coronary Stenosis / epidemiology,  radiography
Hypertension / blood*,  epidemiology
Insulin Resistance / physiology
Middle Aged
Triglycerides / blood*
Reg. No./Substance:

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