Document Detail


High-throughput identification of chemical endomembrane cycling disruptors utilizing tobacco pollen.
MedLine Citation:
PMID:  24306867     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Endomembrane cycling processes in plants remain mostly intractable through classical genetic interrogation. Chemical disruption of these processes provides an opportunity to slow or inhibit these processes for study. Tobacco pollen, which is dependent upon endomembrane cycling for tube growth, provides a plant system that is amenable to high-throughput screening of chemical disruptors. We describe here the process that allowed the identification of over 360 endomembrane cycling disruptors.
Authors:
Michelle Q Brown; Nolan Ung; Natasha V Raikhel; Glenn R Hicks
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Methods in molecular biology (Clifton, N.J.)     Volume:  1056     ISSN:  1940-6029     ISO Abbreviation:  Methods Mol. Biol.     Publication Date:  2014  
Date Detail:
Created Date:  2013-12-05     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9214969     Medline TA:  Methods Mol Biol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  111-4     Citation Subset:  IM    
Affiliation:
Department of Botany and Plant Sciences, Center for Plant Cell Biology, University of California, Riverside, CA, USA.
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