Document Detail

High temporal resolution OCT using image-based retrospective gating.
MedLine Citation:
PMID:  19550478     Owner:  NLM     Status:  MEDLINE    
High temporal resolution OCT imaging is very advantageous for analyzing cardiac mechanics in the developing embryonic heart of small animals. An image-based retrospective gating technique is presented to increase the effective temporal resolution of an OCT system and to allow visualization of systolic dynamics in 3D. The gating technique employs image similarity measures for rearranging asynchronously acquired input data consisting of a time series of 2D images at each z position along the heart volume, to produce a time sequence of 3D volumes of the beating heart. The study includes a novel robust validation technique, which quantitatively evaluates the accuracy of the gating technique, in addition to visual evaluations by 2D multiplanar reformatting (MPR) and 3D volume rendering. The retrospective gating and validation is demonstrated on a stage 14 embryonic quail heart data set. Using the validation scheme, it is shown that the gating is accurate within a standard deviation of 4.7 ms, which is an order of magnitude shorter than the time interval during which systolic contraction (approximately 50 ms) occurs in the developing embryo. This gating method has allowed, for the first time, clear visualization of systolic dynamics of the looping embryonic heart in 3D.
Madhusudhana Gargesha; Michael W Jenkins; David L Wilson; Andrew M Rollins
Related Documents :
1746788 - Three dimensional vascular ultrasound imaging.
9840658 - Voxeline: a software program for 3d real-time visualization of biomedical images.
1571928 - 3d-surface reconstruction of intravascular ultrasound images using personal computer ha...
9112468 - Automatic three-dimensional expansion of structures applied to determination of the cli...
25248178 - Fast x-ray ct image reconstruction using a linearized augmented lagrangian method with ...
15839268 - Signal recovery from autocorrelation and cross-correlation data.
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Optics express     Volume:  17     ISSN:  1094-4087     ISO Abbreviation:  Opt Express     Publication Date:  2009 Jun 
Date Detail:
Created Date:  2009-06-24     Completed Date:  2009-08-25     Revised Date:  2014-09-24    
Medline Journal Info:
Nlm Unique ID:  101137103     Medline TA:  Opt Express     Country:  United States    
Other Details:
Languages:  eng     Pagination:  10786-99     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Embryo, Nonmammalian / pathology*
Heart / embryology*
Image Processing, Computer-Assisted / methods
Imaging, Three-Dimensional / methods*
Models, Statistical
Retrospective Studies
Tomography, Optical Coherence / instrumentation*,  methods*
Grant Support
C06 RR12463-01/RR/NCRR NIH HHS; R01 HL083048/HL/NHLBI NIH HHS; R01 HL083048-01/HL/NHLBI NIH HHS; R01 HL083048-02/HL/NHLBI NIH HHS; R01 HL083048-03/HL/NHLBI NIH HHS; R01HL083048/HL/NHLBI NIH HHS; T32 EB007509/EB/NIBIB NIH HHS; T32 EB007509-01/EB/NIBIB NIH HHS; T32 EB007509-02/EB/NIBIB NIH HHS; T32EB007509/EB/NIBIB NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Origin of light-deflection in lithium niobate and lithium tantalate under electric field.
Next Document:  Optical magnetic plasma in artificial flowers.