| High-speed, ultrahigh resolution optical coherence tomography of the retina in Hunter syndrome. | |
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MedLine Citation:
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PMID: 17955852 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 42-year-old man with Hunter syndrome developed bilateral visual field loss. Visual field testing demon-strated bilateral ring scotomata that corresponded to areas of thinning seen on standard resolution optical coherence tomography. High-speed, ultrahigh resolution optical coherence tomography, capable of 3.5-micron axial resolution, showed a loss of photoreceptors outside the fovea and cystoid spaces within the inner nuclear, ganglion cell, and outer nuclear layers. These results were consistent with histopathologic features that have been reported previously in patients with Hunter syndrome. Optical coherence tomography could be used as a diagnostic modality to monitor patients with Hunter syndrome and to detect subclinical forms of disease. |
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Authors:
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Michael K Yoon; Royce W Chen; Thomas R Hedges; Vivek J Srinivasan; Iwona Gorczynska; James G Fujimoto; Maciej Wojtkowski; Joel S Schuman; Jay S Duker |
Publication Detail:
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Type: Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
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Title: Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye Volume: 38 ISSN: 1542-8877 ISO Abbreviation: Ophthalmic Surg Lasers Imaging Publication Date: 2007 Sep-Oct |
Date Detail:
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Created Date: 2007-10-24 Completed Date: 2007-11-13 Revised Date: 2011-05-05 |
Medline Journal Info:
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Nlm Unique ID: 101155780 Medline TA: Ophthalmic Surg Lasers Imaging Country: United States |
Other Details:
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Languages: eng Pagination: 423-8 Citation Subset: IM |
Affiliation:
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New England Eye Center, Tufts-New England Medical Center, Tufts University, Boston, Massachusetts 02111, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Fluorescein Angiography Fundus Oculi Humans Male Mucopolysaccharidosis II / diagnosis*, physiopathology Optic Disk / pathology Tomography, Optical Coherence / methods* Visual Field Tests Visual Fields |
| Grant Support | |
ID/Acronym/Agency:
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P30 EY008098-20/EY/NEI NIH HHS; P30 EY013078-05/EY/NEI NIH HHS; R01 EY011289-20/EY/NEI NIH HHS; R01 EY013178-07/EY/NEI NIH HHS; R01-EY13178-06/EY/NEI NIH HHS |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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