Document Detail

High-spatial-resolution multistation MR angiography with parallel imaging and blood pool contrast agent: initial experience.
MedLine Citation:
PMID:  17032914     Owner:  NLM     Status:  MEDLINE    
The purpose of this study was to prospectively evaluate the diagnostic accuracy of reader detection of 75% or greater stenosis at high-spatial-resolution multistation magnetic resonance (MR) angiography performed with matrix coils and a blood pool contrast agent. Ten healthy volunteers and 10 patients were examined. All participants provided informed consent to participate in this institutional review board-approved study. For contrast agent-enhanced multistation MR angiography, an albumin-binding gadolinium chelate, gadofosveset trisodium, was used. Imaging was performed during the first-pass and steady-state phases of the contrast agent. Vessel conspicuity on the first-pass MR angiograms obtained in both volunteers and patients was rated as excellent for 93% of vessels. At steady-state imaging, vessel conspicuity was rated as excellent or good for 89% of vessels. Gadofosveset trisodium-enhanced MR angiography yielded sensitivities of 100% and 97% and specificities of 96% and 97% for detection of significant disease in the carotid and lower extremity arteries, respectively.
Konstantin Nikolaou; Harald Kramer; Christina Grosse; Dirk Clevert; Olaf Dietrich; Mike Hartmann; Paul Chamberlin; Stefan Assmann; Maximilian F Reiser; Stefan O Schoenberg
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2006-10-10
Journal Detail:
Title:  Radiology     Volume:  241     ISSN:  0033-8419     ISO Abbreviation:  Radiology     Publication Date:  2006 Dec 
Date Detail:
Created Date:  2006-11-20     Completed Date:  2007-01-05     Revised Date:  2013-11-13    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  861-72     Citation Subset:  AIM; IM    
Copyright Information:
(c) RSNA, 2006.
Department of Clinical Radiology, Ludwig-Maximilians University of Munich, Grosshadern Campus, Marchioninistr 15, 81377 Munich, Germany.
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MeSH Terms
Arterial Occlusive Diseases / diagnosis*
Contrast Media
Gadolinium / diagnostic use*
Magnetic Resonance Angiography / methods*
Middle Aged
Organometallic Compounds / diagnostic use*
Prospective Studies
Sensitivity and Specificity
Reg. No./Substance:
0/Contrast Media; 0/Organometallic Compounds; 7440-54-2/Gadolinium; XM33Q67UVH/gadofosveset trisodium

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