| High-spatial-resolution multistation MR angiography with parallel imaging and blood pool contrast agent: initial experience. | |
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MedLine Citation:
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PMID: 17032914 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The purpose of this study was to prospectively evaluate the diagnostic accuracy of reader detection of 75% or greater stenosis at high-spatial-resolution multistation magnetic resonance (MR) angiography performed with matrix coils and a blood pool contrast agent. Ten healthy volunteers and 10 patients were examined. All participants provided informed consent to participate in this institutional review board-approved study. For contrast agent-enhanced multistation MR angiography, an albumin-binding gadolinium chelate, gadofosveset trisodium, was used. Imaging was performed during the first-pass and steady-state phases of the contrast agent. Vessel conspicuity on the first-pass MR angiograms obtained in both volunteers and patients was rated as excellent for 93% of vessels. At steady-state imaging, vessel conspicuity was rated as excellent or good for 89% of vessels. Gadofosveset trisodium-enhanced MR angiography yielded sensitivities of 100% and 97% and specificities of 96% and 97% for detection of significant disease in the carotid and lower extremity arteries, respectively. |
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Authors:
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Konstantin Nikolaou; Harald Kramer; Christina Grosse; Dirk Clevert; Olaf Dietrich; Mike Hartmann; Paul Chamberlin; Stefan Assmann; Maximilian F Reiser; Stefan O Schoenberg |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2006-10-10 |
Journal Detail:
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Title: Radiology Volume: 241 ISSN: 0033-8419 ISO Abbreviation: Radiology Publication Date: 2006 Dec |
Date Detail:
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Created Date: 2006-11-20 Completed Date: 2007-01-05 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0401260 Medline TA: Radiology Country: United States |
Other Details:
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Languages: eng Pagination: 861-72 Citation Subset: AIM; IM |
Copyright Information:
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(c) RSNA, 2006. |
Affiliation:
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Department of Clinical Radiology, Ludwig-Maximilians University of Munich, Grosshadern Campus, Marchioninistr 15, 81377 Munich, Germany. Konstantin.Nikolaou@med.uni-muenchen.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Arterial Occlusive Diseases / diagnosis* Contrast Media Gadolinium / diagnostic use* Humans Magnetic Resonance Angiography / methods* Male Middle Aged Organometallic Compounds / diagnostic use* Prospective Studies Sensitivity and Specificity |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 0/Organometallic Compounds; 0/gadofosveset trisodium; 7440-54-2/Gadolinium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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