Document Detail


High serum total cholesterol--an indicator for monitoring cholesterol lowering efforts: U.S. adults, 2005-2006.
MedLine Citation:
PMID:  19389314     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Elevated serum total cholesterol is a major and modifiable risk factor for heart disease, the lead-ing cause of death in the United States (1,2). Reducing mean total serum cholesterol levels among adults to less than 200 mg/dL and reducing the proportion who have levels of 240 mg/dL or higher to less than 17% are national Healthy People 2010 objectives (3). Age-adjusted mean serum cholesterol levels among adults aged 20-74 years declined from 222 mg/dL in 1960-1962 to 203 mg/dL in 1999-2002 (4). Among adults aged 20 years and older, the percent of the population with high serum total cholesterol levels (240 mg/dL or higher) declined from 20% during 1988-1994 to 17% during 1999-2002 (4). In individual patients, a high serum total cholesterol level indicates a potential increased risk for heart disease, but further evaluation of other risk factors and the specific components of cholesterol provide the basis for determining the need for initiating therapeutic lifestyle changes or treatment with medication (5). Low-density-lipoprotein (LDL) is the cholesterol component associated with arterial blockage, and it is the primary clinical target for cholesterol management. High-density-lipoprotein (HDL) may help to protect individuals from developing heart disease. In populations, comparisons of total cholesterol levels over time can show if population groups are experiencing improvement in cholesterol levels, and knowledge of trends in levels of total cholesterol can help identify subgroups where additional prevention efforts may be needed.
Authors:
Susan E Schober; Margaret D Carroll; David A Lacher; Rosemarie Hirsch;
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  NCHS data brief     Volume:  -     ISSN:  1941-4927     ISO Abbreviation:  NCHS Data Brief     Publication Date:  2007 Dec 
Date Detail:
Created Date:  2009-04-24     Completed Date:  2009-05-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101495625     Medline TA:  NCHS Data Brief     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1-8     Citation Subset:  IM    
Affiliation:
Centers for Disease Control and Prevention, National Center for Health Statistics, 3311 Toledo Road, Hyattsville, Maryland 20782, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Age Distribution
Cholesterol / blood*
Female
Healthy People Programs
Heart Diseases / blood*,  epidemiology
Humans
Hypercholesterolemia / blood*,  epidemiology
Male
Mass Screening / methods
Middle Aged
Nutrition Surveys
Prevalence
Risk Factors
Sex Distribution
United States / epidemiology
Young Adult
Chemical
Reg. No./Substance:
57-88-5/Cholesterol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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