| High-sensitivity C-reactive protein is the most effective prognostic measurement of acute coronary events. | |
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MedLine Citation:
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PMID: 12233975 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Inflammation plays a major role in the pathogenesis of arterial atherosclerosis. The stages of atheroma development from early recruitment of leukocytes and fatty streaks to the unstable plaque and finally rupture are mediated by the inflammatory process. Several markers of vascular wall inflammation that can predict future risk of plaque rupture have been identified. However, these lack the specificity of CRP. Numerous large-scale prospective studies established hs-CRP as a strong biochemical marker for the prediction of future first or recurrent coronary events. A Food and Drug Administration-approved method for measuring hs-CRP is currently available. |
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Authors:
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Laurie G Futterman; Louis Lemberg |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: American journal of critical care : an official publication, American Association of Critical-Care Nurses Volume: 11 ISSN: 1062-3264 ISO Abbreviation: Am. J. Crit. Care Publication Date: 2002 Sep |
Date Detail:
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Created Date: 2002-09-17 Completed Date: 2003-01-31 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9211547 Medline TA: Am J Crit Care Country: United States |
Other Details:
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Languages: eng Pagination: 482-6 Citation Subset: IM; N |
Affiliation:
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Department of Medicine, University of Miami School of Medicine, Fla 33101, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Biological Markers
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blood C-Reactive Protein / immunology, metabolism* Clinical Competence Coronary Artery Disease / blood*, immunology Humans Inflammation / blood*, immunology Male Middle Aged Predictive Value of Tests Prognosis Risk Factors Vasculitis / blood |
| Chemical | |
Reg. No./Substance:
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0/Biological Markers; 9007-41-4/C-Reactive Protein |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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