Document Detail

High-sensitivity C-reactive protein is the most effective prognostic measurement of acute coronary events.
MedLine Citation:
PMID:  12233975     Owner:  NLM     Status:  MEDLINE    
Inflammation plays a major role in the pathogenesis of arterial atherosclerosis. The stages of atheroma development from early recruitment of leukocytes and fatty streaks to the unstable plaque and finally rupture are mediated by the inflammatory process. Several markers of vascular wall inflammation that can predict future risk of plaque rupture have been identified. However, these lack the specificity of CRP. Numerous large-scale prospective studies established hs-CRP as a strong biochemical marker for the prediction of future first or recurrent coronary events. A Food and Drug Administration-approved method for measuring hs-CRP is currently available.
Laurie G Futterman; Louis Lemberg
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of critical care : an official publication, American Association of Critical-Care Nurses     Volume:  11     ISSN:  1062-3264     ISO Abbreviation:  Am. J. Crit. Care     Publication Date:  2002 Sep 
Date Detail:
Created Date:  2002-09-17     Completed Date:  2003-01-31     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9211547     Medline TA:  Am J Crit Care     Country:  United States    
Other Details:
Languages:  eng     Pagination:  482-6     Citation Subset:  IM; N    
Department of Medicine, University of Miami School of Medicine, Fla 33101, USA.
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MeSH Terms
Biological Markers / blood
C-Reactive Protein / immunology,  metabolism*
Clinical Competence
Coronary Artery Disease / blood*,  immunology
Inflammation / blood*,  immunology
Middle Aged
Predictive Value of Tests
Risk Factors
Vasculitis / blood
Reg. No./Substance:
0/Biological Markers; 9007-41-4/C-Reactive Protein

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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