Document Detail

[High-risk patients with aortic valve stenosis. Interventional therapy].
MedLine Citation:
PMID:  23324914     Owner:  NLM     Status:  MEDLINE    
Aortic valve stenosis is the most prevalent, clinically significant valvular disorder in adult patients. Surgical valve replacement is the standard therapy for patients with symptomatic and severe aortic stenosis; however, many patients are suboptimal candidates for surgery due to age and co-morbidities. The development of transcatheter aortic valve implantation (TAVI) has broadened the therapeutic options, especially in high-risk patients. The first randomized study comparing surgical valve replacement with TAVI in operable high-risk patients show similar mortality and reduction in symptoms after a 2-year follow-up. These data support the use of this technique in high-risk patients with severe aortic stenosis.
R Bekeredjian; S T Pleger; E Chorianopoulos
Publication Detail:
Type:  English Abstract; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Herz     Volume:  38     ISSN:  1615-6692     ISO Abbreviation:  Herz     Publication Date:  2013 Mar 
Date Detail:
Created Date:  2013-03-08     Completed Date:  2013-08-30     Revised Date:  2013-11-14    
Medline Journal Info:
Nlm Unique ID:  7801231     Medline TA:  Herz     Country:  Germany    
Other Details:
Languages:  ger     Pagination:  118-25     Citation Subset:  IM    
Abteilung Innere Medizin III-Kardiologie, Angiologie und Pneumologie, Medizinische Universitätsklinik Heidelberg, Im Neuenheimer Feld 410, Heidelberg, Germany.
Vernacular Title:
Aortenklappenstenose bei erhöhtem Risiko. Interventionelle Therapie.
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MeSH Terms
Aged, 80 and over
Aortic Valve Stenosis / surgery*
Cardiac Catheterization / instrumentation,  methods*,  trends*
Endovascular Procedures
Heart Valve Prosthesis / trends*
Heart Valve Prosthesis Implantation / instrumentation,  methods*,  trends*
Risk Assessment

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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