| High-risk acute coronary syndrome patients with non-ST-elevation myocardial infarction: definition and treatment. | |
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MedLine Citation:
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PMID: 18592363 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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INTRODUCTION: Early risk stratification of patients with acute coronary syndromes (ACS), unstable angina, or non-ST-elevation myocardial infarction ensures patients receive appropriate care. MATERIALS AND METHODS: Many risk-stratification models have been developed to identify high-risk ACS patients who would benefit most from an early invasive strategy and to determine patients at greater risk for bleeding complications. Although high-risk patients seem to benefit most from a combination of aggressive antithrombotic and early invasive therapies, stratification for risk of bleeding also helps in the choice and dosing of appropriate medical therapy. RESULTS: The effective use of glycoprotein IIb/IIIa inhibitors, in particular, is dependent on accurate risk assessment, whereas the risk-to-benefit ratio of direct thrombin inhibitors in high-risk versus low-risk patients as part of an initial therapy plan requires clarification. Nevertheless, use of the same anticoagulant throughout the care pathway may reduce the rates of death or recurrent myocardial infarction, and bleeding complications. |
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Authors:
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Marc Cohen |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review Date: 2008-07-01 |
Journal Detail:
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Title: Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy Volume: 22 ISSN: 0920-3206 ISO Abbreviation: Cardiovasc Drugs Ther Publication Date: 2008 Oct |
Date Detail:
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Created Date: 2008-09-05 Completed Date: 2009-01-12 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8712220 Medline TA: Cardiovasc Drugs Ther Country: United States |
Other Details:
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Languages: eng Pagination: 407-18 Citation Subset: IM |
Affiliation:
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Cardiac Catheterization Laboratory, Newark Beth Israel Medical Center, 201 Lyons Avenue, Newark, NJ 07112, USA. marcohen@sbhcs.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute Coronary Syndrome
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diagnosis,
physiopathology*,
therapy Algorithms Angina, Unstable / diagnosis, physiopathology, therapy Electrocardiography* Hemorrhage / diagnosis, physiopathology, therapy Humans Myocardial Infarction / diagnosis, physiopathology*, therapy Risk Assessment / methods Risk Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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