Document Detail


High-resolution ultrasonography in gastrointestinal graft-versus-host disease.
MedLine Citation:
PMID:  15526100     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Gastrointestinal graft-versus-host disease (GVHD) is one of the main causes of therapy-related death after allogeneic hemopoietic stem cell transplantation. Early diagnosis and immediate treatment are probably essential for improving clinical outcome. High-resolution sonography allows the evaluation of single bowel wall layers throughout the small and large bowel. We report the sonographic findings of seven consecutive patients with histologically confirmed GVHD grade II-IV of the gastrointestinal tract. The patients were examined sonographically within the 1st week after onset of clinical symptoms. Dilatation of the colon and striking bowel wall thickening were early and common features in these patients. Sonography may become a useful tool for diagnosis of patients with gastrointestinal GVHD. Its role for preclinical diagnosis, grading of severity of disease, and guiding therapy of patients with gastrointestinal GVHD warrants evaluation in prospective studies.
Authors:
C Görg; B Wollenberg; J Beyer; M S Stolte; A Neubauer
Publication Detail:
Type:  Journal Article     Date:  2004-09-01
Journal Detail:
Title:  Annals of hematology     Volume:  84     ISSN:  0939-5555     ISO Abbreviation:  Ann. Hematol.     Publication Date:  2005 Jan 
Date Detail:
Created Date:  2004-12-03     Completed Date:  2005-05-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9107334     Medline TA:  Ann Hematol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  33-9     Citation Subset:  IM    
Affiliation:
Department of Hematology and Oncology, Philipps-University Marburg, Marburg, Germany. Christian.Goerg@med.uni-marburg.de
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MeSH Terms
Descriptor/Qualifier:
Adult
Case-Control Studies
Colon / pathology
Female
Gastrointestinal Diseases / diagnosis,  etiology,  ultrasonography*
Graft vs Host Disease / diagnosis,  ultrasonography*
Hematologic Neoplasms / complications,  therapy
Hematopoietic Stem Cell Transplantation / methods
Humans
Male
Middle Aged
Ultrasonography

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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