Document Detail

High-resolution retinal imaging in young children using a handheld scanner and Fourier-domain optical coherence tomography.
MedLine Citation:
PMID:  19121595     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To test the feasibility and applicability of a handheld probe for Fourier-domain optical coherence tomography (Fd-OCT) retinal imaging in infants and children.
METHODS: Thirty children ages 7 months to 9.9 years, with (10 of 30) or without (20 of 30) retinal pathology, were imaged with Fd-OCT. Imaging was performed under sedation in 10 of 30 children ages 7 months to 3.7 years. A high-resolution Fd-OCT system (axial resolution: 4.5 mum; acquisition speeds: 1000 A-scans/frame, 9 frames/second), constructed at the UC Davis Medical Center, in conjunction with a handheld scanner, was used for retinal imaging.
RESULTS: Useful images were obtained from all selected patients. Image acquisition was possible in a conscious state in children as young as 3 years of age. All children tolerated the tests well. The most challenging situation for young children was the lack of an internal fixation target and the moving scanning line, which usually distracted them from a steady fixation. Despite these problems, image quality was comparable with scans previously obtained from an adult population.
CONCLUSIONS: The flexible handheld scanner in association with high acquisition speed and high-resolution Fd-OCT allows retinal imaging in infants and children. This technology provides high-resolution documentation of retinal structure in a pediatric population for the first time.
Christina Gerth; Robert J Zawadzki; Elise Héon; John S Werner
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Publication Detail:
Type:  Controlled Clinical Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Validation Studies     Date:  2009-01-01
Journal Detail:
Title:  Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus / American Association for Pediatric Ophthalmology and Strabismus     Volume:  13     ISSN:  1528-3933     ISO Abbreviation:  J AAPOS     Publication Date:  2009 Feb 
Date Detail:
Created Date:  2009-02-23     Completed Date:  2009-06-19     Revised Date:  2014-09-15    
Medline Journal Info:
Nlm Unique ID:  9710011     Medline TA:  J AAPOS     Country:  United States    
Other Details:
Languages:  eng     Pagination:  72-4     Citation Subset:  IM    
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MeSH Terms
Child, Preschool
Conscious Sedation
Feasibility Studies
Fixation, Ocular
Patient Compliance
Reproducibility of Results
Retinal Diseases / diagnosis*
Tomography, Optical Coherence / instrumentation*,  methods*,  standards
Grant Support
NEI 014743//PHS HHS; R01 EY014743/EY/NEI NIH HHS; R01 EY014743-05/EY/NEI NIH HHS; R01 EY014743-06/EY/NEI NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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