| High-resolution retinal imaging in young children using a handheld scanner and Fourier-domain optical coherence tomography. | |
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MedLine Citation:
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PMID: 19121595 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To test the feasibility and applicability of a handheld probe for Fourier-domain optical coherence tomography (Fd-OCT) retinal imaging in infants and children. METHODS: Thirty children ages 7 months to 9.9 years, with (10 of 30) or without (20 of 30) retinal pathology, were imaged with Fd-OCT. Imaging was performed under sedation in 10 of 30 children ages 7 months to 3.7 years. A high-resolution Fd-OCT system (axial resolution: 4.5 mum; acquisition speeds: 1000 A-scans/frame, 9 frames/second), constructed at the UC Davis Medical Center, in conjunction with a handheld scanner, was used for retinal imaging. RESULTS: Useful images were obtained from all selected patients. Image acquisition was possible in a conscious state in children as young as 3 years of age. All children tolerated the tests well. The most challenging situation for young children was the lack of an internal fixation target and the moving scanning line, which usually distracted them from a steady fixation. Despite these problems, image quality was comparable with scans previously obtained from an adult population. CONCLUSIONS: The flexible handheld scanner in association with high acquisition speed and high-resolution Fd-OCT allows retinal imaging in infants and children. This technology provides high-resolution documentation of retinal structure in a pediatric population for the first time. |
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Authors:
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Christina Gerth; Robert J Zawadzki; Elise Héon; John S Werner |
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Publication Detail:
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Type: Controlled Clinical Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Validation Studies Date: 2009-01-01 |
Journal Detail:
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Title: Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus / American Association for Pediatric Ophthalmology and Strabismus Volume: 13 ISSN: 1528-3933 ISO Abbreviation: J AAPOS Publication Date: 2009 Feb |
Date Detail:
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Created Date: 2009-02-23 Completed Date: 2009-06-19 Revised Date: 2011-05-16 |
Medline Journal Info:
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Nlm Unique ID: 9710011 Medline TA: J AAPOS Country: United States |
Other Details:
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Languages: eng Pagination: 72-4 Citation Subset: IM |
Affiliation:
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Department of Ophthalmology and Vision Sciences, The Hospital for Sick Children and University of Toronto, Toronto, Canada. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Child Child, Preschool Conscious Sedation Feasibility Studies Fixation, Ocular Humans Infant Patient Compliance Posture Reproducibility of Results Retinal Diseases / diagnosis* Tomography, Optical Coherence / instrumentation*, methods*, standards |
| Grant Support | |
ID/Acronym/Agency:
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NEI 014743//PHS HHS; R01 EY014743-05/EY/NEI NIH HHS; R01 EY014743-06/EY/NEI NIH HHS |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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