| High-resolution phase-contrast MRI of aortic and pulmonary blood flow during rest and physical exercise using a MRI compatible bicycle ergometer. | |
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MedLine Citation:
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PMID: 20674204 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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PURPOSE: To establish high-resolution phase-contrast magnetic resonance imaging (PC-MRI) using a MRI compatible bicycle ergometer to quantify aortic and pulmonary blood flow during resting conditions and exercise. MATERIALS AND METHODS: In 20 healthy volunteers (mean age, 26.8±5.0 years) high-resolution PC-MRI (mean temporal resolution, 7.4±3.2ms) was performed in the ascending aorta (AA) and main pulmonary artery (PA) during physical rest and three exercise stages: stage 1, no-load operation; stage 2, heart rate increase 40% compared to rest; stage 3, heart rate increase 80% compared to rest. Flow quantification in AA and PA included flow volume (FV), average velocity (AV), peak velocity (PV) and time to PV (TP). RESULTS: In stage 1 only TP demonstrated a significant change. With progression to stage 2, all parameters altered significantly. Flow measurements during stage 3 evidenced further alterations only of AV and TP regarding both AA and PA. The deviation of the heart rate from the desired target value was significantly higher for stage 3 compared to stage 2, and 15% of the subjects did not reach the desired target heart rate of stage 3 at all. CONCLUSION: Flow quantification by high-resolution PC-MRI during exercise using a MRI compatible bicycle ergometer is feasible. Medium exercise stages are necessary and sufficient to demonstrate flow alterations in healthy volunteers. PC-MRI ergometry may give insights into aberrant hemodynamic conditions in patients with cardiovascular and pulmonary disease. |
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Authors:
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Tim Frederik Weber; Hendrik von Tengg-Kobligk; Annette Kopp-Schneider; Julia Ley-Zaporozhan; Hans-Ulrich Kauczor; Sebastian Ley |
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Publication Detail:
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Type: Journal Article Date: 2010-07-31 |
Journal Detail:
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Title: European journal of radiology Volume: 80 ISSN: 1872-7727 ISO Abbreviation: Eur J Radiol Publication Date: 2011 Oct |
Date Detail:
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Created Date: 2011-09-13 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8106411 Medline TA: Eur J Radiol Country: Ireland |
Other Details:
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Languages: eng Pagination: 103-8 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Elsevier Ireland Ltd. All rights reserved. |
Affiliation:
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Department of Diagnostic and Interventional Radiology, University Medical Center Heidelberg, INF 110, 69120 Heidelberg, Germany; Department of Radiology, German Cancer Research Center, INF 280, 69120 Heidelberg, Germany. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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