Document Detail

High-resolution imaging of the spine using multidetector-row computed tomography: differentiation between benign and malignant vertebral compression fractures.
MedLine Citation:
PMID:  16163049     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The purpose of this study was to investigate the ability of high-resolution computed tomography (CT) images to distinguish between benign and malignant vertebral compression fractures. METHODS: Computed tomography images of 45 benign compression fractures in 40 patients and 33 malignant compression fractures in 33 patients were evaluated. A 16-slice multidetector-row CT scanner was used for data acquisition, and axial images with a slice thickness of 1 mm and sagittal and coronal multiplanar reconstruction images with a slice thickness of 0.7 to 1 mm were used for interpretation. RESULTS: The following findings were significantly more frequent in malignant fractures: destruction of the anterolateral and/or posterior cortex of the vertebral body, destruction of the cancellous bone of the vertebral body, destruction of the end plate, destruction of the pedicle, a paraspinal soft tissue mass, and an epidural mass. The extremely reliable signs of malignancy were destruction of the anterolateral and/or posterior cortex of vertebral body (100% accuracy) and destruction of the cancellous bone of the vertebral body (97.4% accuracy). CONCLUSION: High-resolution CT can provide many useful signs for differentiating between benign and malignant vertebral compression fractures, and its diagnostic ability is sufficient for clinical use.
Takao Kubota; Kei Yamada; Hirotoshi Ito; Osamu Kizu; Tsunehiko Nishimura
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of computer assisted tomography     Volume:  29     ISSN:  0363-8715     ISO Abbreviation:  J Comput Assist Tomogr     Publication Date:    2005 Sep-Oct
Date Detail:
Created Date:  2005-09-15     Completed Date:  2005-11-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7703942     Medline TA:  J Comput Assist Tomogr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  712-9     Citation Subset:  IM    
Department of Radiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto, Japan.
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MeSH Terms
Aged, 80 and over
Chi-Square Distribution
Contrast Media
Diagnosis, Differential
Iopamidol / diagnostic use
Middle Aged
Spinal Fractures / etiology,  radiography*,  radionuclide imaging
Spinal Neoplasms / complications,  radiography*,  radionuclide imaging
Tomography, X-Ray Computed / methods*
Reg. No./Substance:
0/Contrast Media; 62883-00-5/Iopamidol

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