| High-resolution 7T MRI of the human hippocampus in vivo. | |
| | |
MedLine Citation:
|
PMID: 18972336 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
PURPOSE: To describe an initial experience imaging the human hippocampus in vivo using a 7T magnetic resonance (MR) scanner and a protocol developed for very high field neuroimaging. MATERIALS AND METHODS: Six normal subjects were scanned on a 7T whole body MR scanner equipped with a 16-channel head coil. Sequences included a full field of view T1-weighted 3D turbo field echo (T1W 3D TFE: time of acquisition (TA)=08:58), T2*-weighted 2D fast field echo (T2*W 2D FFE: TA=05:20), and susceptibility-weighted imaging (SWI: TA=04:20). SWI data were postprocessed using a minimum intensity projection (minIP) algorithm. Total imaging time was 23 minutes. RESULTS: T1W 3D TFE images with 700 microm isotropic voxels provided excellent anatomic depiction of macroscopic hippocampal structures. T2*W 2D FFE images with 0.5 mm in-plane resolution and 2.5 mm slice thickness provided clear discrimination of the Cornu Ammonis and the compilation of adjacent sublayers of the hippocampus. SWI images (0.5 mm in-plane resolution, 1.0 mm slice thickness) delineated microvenous anatomy of the hippocampus. CONCLUSION: In vivo 7T MR imaging can take advantage of higher signal-to-noise and novel contrast mechanisms to provide increased conspicuity of hippocampal anatomy. |
| | |
Authors:
|
Bradley P Thomas; E Brian Welch; Blake D Niederhauser; William O Whetsell; Adam W Anderson; John C Gore; Malcolm J Avison; Jeffrey L Creasy |
Related Documents
:
|
15349696 - Volume variation of mastoid pneumatization in different age groups: a study by three-di... 7601816 - Technical foundations of spiral ct. 16460476 - Virtual gastroscopy: initial attempt in north american patients. 20972936 - [protocol optimization of three-dimensional spiral ct of craniofacial bones]. 20365876 - Magnetic-field decay of three interlocked flux rings with zero linking number. 11770916 - Truly hybrid interventional mr/x-ray system: investigation of in vivo applications. |
Publication Detail:
|
Type: Journal Article; Research Support, N.I.H., Extramural |
Journal Detail:
|
Title: Journal of magnetic resonance imaging : JMRI Volume: 28 ISSN: 1053-1807 ISO Abbreviation: J Magn Reson Imaging Publication Date: 2008 Nov |
Date Detail:
|
Created Date: 2008-11-03 Completed Date: 2009-01-22 Revised Date: 2010-12-03 |
Medline Journal Info:
|
Nlm Unique ID: 9105850 Medline TA: J Magn Reson Imaging Country: United States |
Other Details:
|
Languages: eng Pagination: 1266-72 Citation Subset: IM |
Copyright Information:
|
Copyright (c) 2008 Wiley-Liss, Inc. |
Affiliation:
|
Vanderbilt University Medical Center, Department of Radiology and Radiological Sciences, Nashville, Tennessee 37232-2675, USA. bradley.thomas@vanderbilt.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Algorithms* Hippocampus / anatomy & histology* Humans Image Enhancement / methods* Image Interpretation, Computer-Assisted / methods* Magnetic Resonance Imaging / methods* Male Middle Aged Reproducibility of Results Sensitivity and Specificity |
| Grant Support | |
ID/Acronym/Agency:
|
R01 EB000461-07/EB/NIBIB NIH HHS; R01EB000461/EB/NIBIB NIH HHS; S10 RR023047-01/RR/NCRR NIH HHS |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Method for rapid calculation of quantitative cerebral perfusion.
Next Document: Inflow quantification in three-dimensional cardiovascular MR imaging.