| High reproducibility of regional abnormalities on interictal 123I-IMP SPECT brain scans in adults with partial epilepsy. | |
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MedLine Citation:
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PMID: 2147904 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The reproducibility of two N-isopropyl-(iodine 123) p-iodoamphetamine (123I-IMP single photon emission computed tomography (SPECT) scans both taken during interictal periods was studied in 13 adult patients with partial epilepsy who had normal CT scans. The frequency of the seizures and the nature of the ictal symptoms were virtually unchanged during the interval between the two SPECT scans performed in each case. In 8 (72.7%) of 11 patients who had abnormal images consisting of focal hypofixation images of 123I-IMP, i.e. zones of decreased regional cerebral blood flow on the first scans, complete or partial regional reproduction of the SPECT abnormalities was observed. This high reproducibility supports the usefulness of SPECT scans in the regional diagnosis of epileptic foci. |
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Authors:
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I Jibiki; T Kubota; K Fujimoto; N Yamaguchi; H Matsuda; S Tsuji; K Hisada |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: European archives of psychiatry and clinical neuroscience Volume: 240 ISSN: 0940-1334 ISO Abbreviation: Eur Arch Psychiatry Clin Neurosci Publication Date: 1990 |
Date Detail:
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Created Date: 1991-01-28 Completed Date: 1991-01-28 Revised Date: 2009-05-11 |
Medline Journal Info:
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Nlm Unique ID: 9103030 Medline TA: Eur Arch Psychiatry Clin Neurosci Country: GERMANY |
Other Details:
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Languages: eng Pagination: 5-8 Citation Subset: IM |
Affiliation:
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Department of Neuropsychiatry, Kanazawa University School of Medicine, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Amphetamines
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diagnostic use* Cerebral Cortex / radionuclide imaging Electroencephalography / methods Epilepsies, Partial / radionuclide imaging* Epilepsy, Temporal Lobe / radionuclide imaging Evoked Potentials / physiology Female Humans Iodine Radioisotopes / diagnostic use* Iofetamine Male Tomography, Emission-Computed, Single-Photon / methods* |
| Chemical | |
Reg. No./Substance:
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0/Amphetamines; 0/Iodine Radioisotopes; 95896-48-3/Iofetamine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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