| High procalcitonin in a patient with drug hypersensitivity syndrome. | |
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MedLine Citation:
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PMID: 19687601 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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We present a patient who developed carbamazepine (CBZ)-induced Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) syndrome associated with high serum procalcitonin (PCT). The presentation (high fever, hepatosplenomegaly, leukocytosis), high PCT and CRP initially suggested sepsis, and he was treated with antibiotics, while CBZ was continued. The rash and hepatitis worsened. After withdrawal of CBZ, corticosteroid therapy was administered and the patient recovered with normalization of PCT. This case demonstrates that PCT may be increased in patients with DRESS. This is the first report of CBZ-induced DRESS associated with high PCT, and the second case of increased PCT in DRESS. |
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Authors:
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Branka Bonaci-Nikolic; Ivica Jeremic; Milos Nikolic; Sladjana Andrejevic; Lidija Lavadinovic |
Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't Date: 2009-08-17 |
Journal Detail:
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Title: Internal medicine (Tokyo, Japan) Volume: 48 ISSN: 1349-7235 ISO Abbreviation: Intern. Med. Publication Date: 2009 |
Date Detail:
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Created Date: 2009-08-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9204241 Medline TA: Intern Med Country: Japan |
Other Details:
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Languages: eng Pagination: 1471-4 Citation Subset: IM |
Affiliation:
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Institute of Allergy and Clinical Immunology, Clinical Center of Serbia, Belgrade, Serbia. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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