Document Detail

High prevalence of vitamin D deficiency in Pakistani mothers and their newborns.
MedLine Citation:
PMID:  21247568     Owner:  NLM     Status:  Publisher    
OBJECTIVE: To determine the prevalence of vitamin D deficiency in Pakistani parturients and their newborns and to assess the correlation between maternal and newborn serum levels of the vitamin D metabolite 25-hydroxy vitamin D3. METHODS: A prospective study of parturients presenting to the labor suite with a singleton pregnancy. Maternal and cord blood were collected for estimation of serum 25-hydroxy vitamin D3. RESULTS: In total, 89% of the gravidae were deficient in vitamin D (serum 25-hydroxy vitamin D3 <30ng/mL). There was a positive correlation between maternal and cord blood 25-hydroxy vitamin D3 levels(r=0.68; P<0.001). Inverse correlations were noted between cord blood 25-hydroxy vitamin D3 and a longer duration of gestation (r=-0.33; P=0.003) and with the newborn's birth weight (r=-0.23; P=0.048). Maternal 25-hydroxy vitamin D3 levels were inversely correlated with maternal mean arterial pressure (r=0.029; P<0.020). CONCLUSION: There was a high prevalence of vitamin D deficiency in the Pakistani parturients and their newborns. There was a correlation between higher maternal vitamin D levels and lower blood pressure in the mothers.
Nazli Hossain; Rafiq Khanani; Fatima Hussain-Kanani; Tahira Shah; Shaheen Arif; Lubna Pal
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-1-17
Journal Detail:
Title:  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics     Volume:  -     ISSN:  1879-3479     ISO Abbreviation:  -     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-1-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0210174     Medline TA:  Int J Gynaecol Obstet     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2010 International Federation of Gynecology and Obstetrics. All rights reserved.
Department of Obstetrics and Gynecology, Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
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