| High prevalence of thyroid nodules in patients with achrocordons (skin tags). Possible role of insulin-resistance. | |
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MedLine Citation:
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PMID: 19622476 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Due to the observation of a great number of patients having achrocordons, when they underwent fine needle biopsies for thyroid nodules, we decided to perform a prospective study to investigate the relationship between this finding and the presence of insulin resistance (IR), since achrocordons are commonly seen in hyperinsulinemic subjects. A total of 120 consecutive women, aged 18-35 yrs were studied. All subjects were also evaluated by thyroid ultrasound (US) for measuring thyroid volume and the presence of non-palpable nodules. Basal and post-prandial serum insulin was measured in all of them, as well as the Homeostasis Model Assessment (HOMA). Subjects were divided in two groups: Group A, with achrocordons (n = 44) and Group B, without achrocordons (n = 76). Group A showed 24 patients (54.5%) with thyroid nodules, whereas Group B only 13 subjects (17.1%); p = 0.0087. When we considered, as having high normal thyroid volume, the glands weighting more than 16 grams by US, without nodules, it was found that 8/44 cases from Group A (18.6%) and 3/76 from Group B (3.9%) fitted in such category, p = 0.0076. In patients with nodules and/or bigger thyroids, IR was observed in 36/44 (81.8%) of Group A and 14/76 (18.4%) of Group B, p = 0.0069, while the overall prevalence of IR was 0.47 in Group A and 0.05 in Group B, p = 0.00094. It is concluded that patients with achrocordons have a higher prevalence of US-detected thyroid nodules and larger thyroid glands. Then, it may be beneficial to search for thyroid abnormalities in those subjects with skin tags. |
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Authors:
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Jorge Rezzónico; Mariana Rezzónico; Eduardo Pusiol; Fabián Pitoia; Hugo Niepomniszcze |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Medicina Volume: 69 ISSN: 0025-7680 ISO Abbreviation: Medicina (B Aires) Publication Date: 2009 |
Date Detail:
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Created Date: 2009-07-22 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0204271 Medline TA: Medicina (B Aires) Country: Argentina |
Other Details:
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Languages: eng Pagination: 302-4 Citation Subset: IM |
Affiliation:
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Centro Privado de Endocrinología, Mendoza. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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