Document Detail

High prevalence of restless legs syndrome among patients with polycytemia vera treated with venesectio.
MedLine Citation:
PMID:  19225914     Owner:  NLM     Status:  MEDLINE    
In order to examine whether symptoms of iron deficiency anemia are due to the iron deficiency itself or the associated anemia, 34 patients with polycytemia vera (PV) treated with venesectio, who had iron deficiency but normal hemoglobin (Hb) levels, were given a questionnaire covering symptoms of iron deficiency including the international RLS-scale and the Fact-fatigue quality of life scale (QoL). We found a prevalence of pica of 11.7%, mouth paresthesias of 5.8% and rest-less legs 29.6% (RLS "normal" prevalence 10%). Thus, the prevalence of RLS is significantly higher in our population. We also saw a significant difference in QoL between patients with and without RLS (P = 0.015) and QoL correlated with the severity of RLS (R = 0.85). In conclusion, RLS seems to be a frequent and serious problem for PV patients treated with venesectio according to standard guidelines.
Magnus Tobiasson; Bassam Alyass; Susanne S?derlund; Gunnar Birgeg?rd
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Publication Detail:
Type:  Journal Article     Date:  2009-02-19
Journal Detail:
Title:  Medical oncology (Northwood, London, England)     Volume:  27     ISSN:  1559-131X     ISO Abbreviation:  Med. Oncol.     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-03-03     Completed Date:  2010-06-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9435512     Medline TA:  Med Oncol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  105-7     Citation Subset:  IM    
M?larsjukhuset, Eskilstuna, S?rmlands l?ns landsting, Sweden.
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MeSH Terms
Anemia, Iron-Deficiency / etiology,  physiopathology
Health Surveys
Iron / deficiency
Mouth / physiopathology
Paresthesia / epidemiology,  etiology
Phlebotomy / adverse effects*
Pica / epidemiology,  etiology
Polycythemia Vera / complications,  physiopathology,  therapy*
Quality of Life
Restless Legs Syndrome* / epidemiology,  etiology
Reg. No./Substance:

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