| High prevalence of important cardiac findings in patients with peripheral arterial disease referred for echocardiography. | |
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MedLine Citation:
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PMID: 16084337 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Patients with peripheral arterial disease (PAD) diagnosed by ankle-brachial index evaluation are known to have high cardiovascular mortality. Although this has primarily been attributed to coexistent coronary artery disease, the prevalence of abnormal echocardiographic findings for patients with PAD has not been studied. Our goal was to study the association between PAD and clinically important echocardiographic findings in symptomatic patients with PAD referred for echocardiography. METHODS: Eligible patients were identified from a database of 615 consecutive patients referred for clinically indicated ankle-brachial index evaluation in our vascular laboratory. Patients were included (n = 309) if they also had a complete transthoracic echocardiogram in the digital echocardiogram database at our institution. Final transthoracic echocardiographic reports were retrospectively reviewed for study indication and clinically important echocardiographic findings. Patients with PAD (ankle-brachial index < 0.9) (n = 190) were compared with patients without PAD (n = 119). RESULTS: Patients with PAD were found to have a high prevalence of clinically important echocardiographic findings, and significantly more clinically important echocardiographic findings (61.6% vs 35.3%, P < .001), including more left ventricular (LV) dysfunction and aortic stenosis, than patients without PAD. On multivariate logistic regression analysis, the presence of PAD was found to be an independent predictor of LV ejection fraction < 50% (odds ratio 2.86, 95% confidence interval 1.54-5.32, P = .001), LV ejection fraction < 35% (odds ratio 2.48, 95% confidence interval 1.22-5.07, P = .02), and any clinically important echocardiographic finding (odds ratio 2.65, 95% confidence interval 1.61-4.36, P < .001). CONCLUSION: In symptomatic patients with PAD referred for echocardiography, there is a high prevalence of clinically important echocardiographic findings, including LV dysfunction, and PAD appears to be an independent predictor of an abnormal echocardiogram. These findings suggest that a prospective echocardiographic screening study in symptomatic patients with PAD is warranted. |
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Authors:
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R Parker Ward; James K Min; Kris M McDonough; Roberto M Lang |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography Volume: 18 ISSN: 1097-6795 ISO Abbreviation: J Am Soc Echocardiogr Publication Date: 2005 Aug |
Date Detail:
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Created Date: 2005-08-08 Completed Date: 2006-03-31 Revised Date: 2007-11-02 |
Medline Journal Info:
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Nlm Unique ID: 8801388 Medline TA: J Am Soc Echocardiogr Country: United States |
Other Details:
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Languages: eng Pagination: 844-9 Citation Subset: IM |
Affiliation:
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Department of Medicine, University of Chicago, Chicago, Illinois, USA. pward@medicine.bsd.uchicago.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Aortic Valve Stenosis / complications*, ultrasonography Echocardiography Female Heart Diseases / complications, ultrasonography Humans Logistic Models Male Middle Aged Multivariate Analysis Peripheral Vascular Diseases / complications* Prevalence Retrospective Studies Risk Factors Ventricular Dysfunction, Left / complications*, ultrasonography |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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