| High prevalence of human cytomegalovirus in a population of periodontally healthy subjects. | |
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MedLine Citation:
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PMID: 20038920 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Human cytomegalovirus (HCMV) appears to be more frequent in periodontally affected patients than in healthy control groups. Based on this assumption, it has been suggested that HCMV may play a role in the pathogenesis of periodontal disease. OBJECTIVE: The objective of this uncontrolled study was to assess the occurrence of HCMV in a large unselected population of periodontally healthy subjects. STUDY DESIGN: Fifty consecutive periodontally healthy patients satisfied the inclusion criteria. Two samples of gingival crevicular fluids were taken from two non-bleeding on probing sites for each patient. Samples were collected from the anterior and the posterior area. Polymerase chain reaction (PCR) was used to identify the presence of HCMV. RESULTS: HCMV was detected in 17 (33%) out of 50 participants. Ten subjects showed presence of HCMV on both anterior and posterior sites, whereas the remaining 7 only had HCMV present in the anterior sites. No differences were noticed between HCMV positive and HCMV negative in terms of smoking (p = 0.33), drinking habits (p=0,94) or the presence of prosthodontic restorations (p= 0,89). CONCLUSIONS: HCMV was detected in a high proportion of periodontally healthy subjects. Its presence was not found to be influenced by smoking or drinking habits. |
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Authors:
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Pier-Luigi Foglio-Bonda; Mario Gabriele; Filippo Graziani; Marco De Andrea; Michele Mondini; Marisa Gariglio |
Publication Detail:
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Type: Journal Article Date: 2010-03-01 |
Journal Detail:
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Title: Medicina oral, patolog?a oral y cirug?a bucal Volume: 15 ISSN: 1698-6946 ISO Abbreviation: Med Oral Patol Oral Cir Bucal Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-03-01 Completed Date: 2010-06-30 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101231694 Medline TA: Med Oral Patol Oral Cir Bucal Country: Spain |
Other Details:
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Languages: eng Pagination: e292-6 Citation Subset: D; IM |
Affiliation:
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Dental Clinic, University of Eastern Piedmont A. Avogadro, Novara, Italy. fbonda@med.unipmn.it |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Cytomegalovirus / isolation & purification* Female Gingiva / virology* Humans Male Middle Aged Prevalence Young Adult |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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