| High-performance liquid chromatography of biologically important, small epimeric peptides and their L, D-amino acid content. | |
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MedLine Citation:
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PMID: 20470244 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Since most of the proteinogenic alpha-amino acids contain a chiral carbon atom, the stereoisomers of both these amino acids and the peptides in which they are to be found may possess differences in biological activity in living systems. The important analytical task of the separation of optical isomers is achieved mainly by chromatographic methods. This special review surveys direct and indirect HPLC separations of biologically important, small epimeric peptides and their L, D-amino acid content. |
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Authors:
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I Ilisz; Z Pataj; A Aranyi; A Péter |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Mini reviews in medicinal chemistry Volume: 10 ISSN: 1875-5607 ISO Abbreviation: Mini Rev Med Chem Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-05-17 Completed Date: 2010-09-17 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101094212 Medline TA: Mini Rev Med Chem Country: Netherlands |
Other Details:
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Languages: eng Pagination: 287-98 Citation Subset: IM |
Affiliation:
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Department of Inorganic and Analytical Chemistry, University of Szeged, H-6720 Szeged, Dóm tér 7, Hungary. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Amino Acid Sequence Amino Acids* Animals Biological Products / chemistry, metabolism Chromatography, High Pressure Liquid / methods* Humans Peptides / chemical synthesis, chemistry*, isolation & purification*, metabolism Stereoisomerism |
| Chemical | |
Reg. No./Substance:
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0/Amino Acids; 0/Biological Products; 0/Peptides |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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