Document Detail

High-performance hemodiafiltration and blood pressure stability.
MedLine Citation:
PMID:  9031267     Owner:  NLM     Status:  MEDLINE    
In the present study, we have estimated plasma nonrefilling rate and assessed its relationship to blood pressure stability during hemodialysis (HD) with normal or high sodium dialysate and during high flux hemodiafiltration (HDF). In standard HD, the greater plasma nonrefilling rate resulted in the larger decrease in blood pressure (alpha = -6.7 +/- 0.2 mm Hg/%, p < 0.01, n = 75). When compared to standard HD, high flux HDF (n = 6) altered neither plasma refilling nor blood pressure stability. Finally, the restrictive usage of high sodium dialysate reduced plasma nonrefilling rate (21 +/- 3 vs. 16 +/- 2%, p < 0.05, n = 10) and the magnitude of decrease in blood pressure (16 +/- 6 vs. 9 +/- 4 mm Hg, p < 0.05) without increase in interdialytic weight gain. Our data indicate relative safety of high performance HDF, and warrant judicious use of high sodium dialysate for the HD patients with hypotensive episodes.
T Takenaka; Y Tsuchiya; H Suzuki
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Nephron     Volume:  75     ISSN:  0028-2766     ISO Abbreviation:  Nephron     Publication Date:  1997  
Date Detail:
Created Date:  1997-04-15     Completed Date:  1997-04-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0331777     Medline TA:  Nephron     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  30-5     Citation Subset:  IM    
Tsuchiya Clinic, Tokyo, Japan.
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MeSH Terms
Blood Pressure / drug effects,  physiology*
Body Weight
Dialysis Solutions / pharmacology,  therapeutic use
Hemodiafiltration* / adverse effects
Hypotension / etiology,  physiopathology
Osmolar Concentration
Plasma / drug effects,  physiology
Sodium / pharmacology,  therapeutic use
Reg. No./Substance:
0/Dialysis Solutions; 7440-23-5/Sodium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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