| High-osmolar and low-osmolar contrast media. An update on frequency of adverse drug reactions. | |
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MedLine Citation:
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PMID: 8489830 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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During the past 3 years a great number of papers about adverse drug reactions to intravascular injection of high-osmolar and low-osmolar iodinated contrast media (CM) have been published. They include observational studies, randomized trials, meta-analyses and committee reports. Thorough analysis of this material substantiates an improvement in safety of at least 6-fold using nonionic low-osmolar CM compared with ionic high-osmolar CM. The point where only a small minority is continuing to argue effectively that low-osmolar CM are not better than conventional high-osmolar CM has now been reached. High-osmolar CM are used less and less for intravascular purposes, and, in fact, have been totally replaced by low-osmolar CM in 4 countries. |
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Authors:
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H S Thomsen; S Dorph |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Acta radiologica (Stockholm, Sweden : 1987) Volume: 34 ISSN: 0284-1851 ISO Abbreviation: Acta Radiol Publication Date: 1993 May |
Date Detail:
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Created Date: 1993-06-16 Completed Date: 1993-06-16 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8706123 Medline TA: Acta Radiol Country: DENMARK |
Other Details:
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Languages: eng Pagination: 205-9 Citation Subset: IM |
Affiliation:
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Department of Diagnostic Radiology, Herlev Hospital, University of Copenhagen, Denmark. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Clinical Trials as Topic Contrast Media / adverse effects*, chemistry* Humans Osmolar Concentration |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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