| High and low frequency electrical stimulation in non-lesional temporal lobe epilepsy. | |
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MedLine Citation:
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PMID: 17582791 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In patients with pharmacologically intractable epilepsy who are not eligible for surgery, deep brain stimulation is currently under evaluation as an alternative treatment. Optimal stimulation parameters, including high (HFS) versus low frequency (LFS) stimulation, are not well defined. Here, we report the effects of HFS (130 pulses per second, pps) and LFS (5pps) of the principal epileptogenic focus, in three patients with non-lesional temporal lobe epilepsy. HFS, but not LFS, was associated with a reduction of the interictal discharges and absence of seizures. HFS may be beneficial in patients with non-lesional temporal lobe epilepsy who are not surgical candidates. |
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Authors:
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Colette Boëx; Serge Vulliémoz; Laurent Spinelli; Claudio Pollo; Margitta Seeck |
Publication Detail:
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Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't Date: 2007-06-19 |
Journal Detail:
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Title: Seizure : the journal of the British Epilepsy Association Volume: 16 ISSN: 1059-1311 ISO Abbreviation: Seizure Publication Date: 2007 Dec |
Date Detail:
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Created Date: 2007-11-05 Completed Date: 2008-02-29 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9306979 Medline TA: Seizure Country: England |
Other Details:
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Languages: eng Pagination: 664-9 Citation Subset: IM |
Affiliation:
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Presurgical Epilepsy Evaluation Unit, Department of Neurology, University Hospital of Geneva, Switzerland. Colette.Boex@hcuge.ch |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Dose-Response Relationship, Radiation Electric Stimulation / methods* Epilepsy, Temporal Lobe / therapy* Female Humans Male |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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