Document Detail


High levels of hippuric acid in the urine of Thai press workers.
MedLine Citation:
PMID:  12693601     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Toluene is an important toxic volatile agent found in many modern industrial processes. Toluene exposure is of particular concern because of the ongoing exposure of thousands of workers in industrial plants and recent research has indicated that toluene/exposure can result in chronic toxicity. The monitoring and control of toluene exposure among at-risk workers is necessary. Urine hippuric acid determination is a helpful test monitoring groups of at-risk workers. In this study, urine samples were obtained from 20 control subjects and 48 press workers from a factory in Bangkok. Each subject gave a specimen of urine; each specimen was analyzed for hippuric acid level by the Ohmori method. The average urine hippuric acid level in the control group was 0.23 +/- 0.15 mg/gCr (range = 0.05 - 0.58 mg/gCr) while that of the experimental group was 0.37 +/- 0.37 mg/gCr (range = 0.06 - 0.18 mg/gCr). A significant higher urine hippuric acid level among the press workers was found (p = 0.03). Based on this study, the prevention of exposure to toluene among high-risk workers is recommended.
Authors:
Viroj Wiwanitkit; Jamsai Suwansaksri; Suriya Srita; Anucha Fongsoongnern
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Southeast Asian journal of tropical medicine and public health     Volume:  33     ISSN:  0125-1562     ISO Abbreviation:  Southeast Asian J. Trop. Med. Public Health     Publication Date:  2002 Sep 
Date Detail:
Created Date:  2003-04-15     Completed Date:  2003-07-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0266303     Medline TA:  Southeast Asian J Trop Med Public Health     Country:  Thailand    
Other Details:
Languages:  eng     Pagination:  624-7     Citation Subset:  IM    
Affiliation:
Department of Laboratory Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.
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MeSH Terms
Descriptor/Qualifier:
Case-Control Studies
Hippurates / urine*
Humans
Occupational Exposure / analysis*,  prevention & control
Thailand
Toluene / adverse effects,  analysis*
Chemical
Reg. No./Substance:
0/Hippurates; 108-88-3/Toluene; 495-69-2/hippuric acid

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