| High levels of congenital transmission of Toxoplasma gondii in longitudinal and cross-sectional studies on sheep farms provides evidence of vertical transmission in ovine hosts. | |
| | |
MedLine Citation:
|
PMID: 15796013 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Recent research suggests that vertical transmission may play an important role in sustaining Toxoplasma gondii infection in some species. We report here that congenital transmission occurs at consistently high levels in pedigree Charollais and outbred sheep flocks sampled over a 3-year period. Overall rates of transmission per pregnancy determined by PCR based diagnosis, were consistent over time in a commercial sheep flock (69%) and in sympatric (60%) and allopatric (41%) populations of Charollais sheep. The result of this was that 53.7 % of lambs were acquiring an infection prior to birth: 46.4% of live lambs and 90.0% of dead lambs (in agreement with the association made between T. gondii and abortion). No significant differences were observed between lamb sexes. Although we cannot distinguish between congenital transmission occurring due to primary infection at pregnancy or reactivation of chronic infection during pregnancy, our observations of consistently high levels of congenital transmission over successive lambings favour the latter. |
| | |
Authors:
|
R H Williams; E K Morley; J M Hughes; P Duncanson; R S Terry; J E Smith; G Hide |
Related Documents
:
|
21315213 - Pregnancy in women with corrected tetralogy of fallot: occurrence and predictors of adv... 1603443 - Effective treatment of chlamydia trachomatis infection during pregnancy to prevent peri... 14998953 - Uterine position at real embryo transfer compared with mock embryo transfer. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Parasitology Volume: 130 ISSN: 0031-1820 ISO Abbreviation: Parasitology Publication Date: 2005 Mar |
Date Detail:
|
Created Date: 2005-03-30 Completed Date: 2005-05-04 Revised Date: 2008-11-21 |
Medline Journal Info:
|
Nlm Unique ID: 0401121 Medline TA: Parasitology Country: England |
Other Details:
|
Languages: eng Pagination: 301-7 Citation Subset: IM |
Affiliation:
|
Centre for Parasitology, Molecular Epidemiology and Ecology, Bioscience Research Institute, School of Environment and Life Sciences, University of Salford, Salford M5 4WT, UK. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Abortion, Veterinary
/
parasitology* Animals Cross-Sectional Studies Infectious Disease Transmission, Vertical / veterinary* Longitudinal Studies Sheep Sheep Diseases / congenital*, epidemiology*, transmission Toxoplasmosis, Animal / congenital*, epidemiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Toxoplasmosis in Pallas' cats (Otocolobus manul) raised in captivity.
Next Document: The role of acidic organelles in the development of schistosomula of Schistosoma mansoni and their r...