Document Detail

High-intensity zone (HIZ) of lumbar intervertebral disc on T2-weighted magnetic resonance images: spatial distribution, and correlation of distribution with low back pain (LBP).
MedLine Citation:
PMID:  22391868     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To analyze the three-dimensional distribution of high-intensity zone (HIZ) in lumbar disks and to assess the correlation between low back pain (LBP) and spatial distribution of HIZs.
METHODS: Clinical records and lumbar MRIs of 623 patients (337 males and 286 females, age 50.10 ± 15.38 years) were selected and reviewed. Baseline characteristics and 3D localization were performed and recorded by two radiologists in a blind fashion.
RESULTS: Among the 623 patients, 200 exhibited an HIZ in at least one disk. HIZs were more frequently seen in the inferior part of annulus fibrosus (superior-middle-inferior ratio 39:59:140, P < 0.001). One hundred and eighty-one HIZs (76.1%) occurred at L4/5 and/or L5/S1. The prevalence of multi-segmental HIZ was 16.5%. Among the 33 patients with multi-segmental HIZs, 24 exhibited HIZs in adjacent disks. The LBP rate of HIZ patients was significantly higher than that of patients who exhibited no HIZ (57.5 vs. 47.8%, P < 0.05). There was no evidence for a correlation between LBP and spatial distribution of HIZ in disk (P > 0.05). The incidence of LBP was slightly higher when the HIZ disk level was lower or when there were HIZs exhibited in more disks; however, the difference was statistically insignificant (P > 0.05).
CONCLUSIONS: High-intensity zones occurred frequently at lower segments, inferior part of annulus fibrosus, and single disk.
Zi-Xuan Wang; You-Gu Hu
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2012-03-04
Journal Detail:
Title:  European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society     Volume:  21     ISSN:  1432-0932     ISO Abbreviation:  Eur Spine J     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-07-04     Completed Date:  2013-01-02     Revised Date:  2013-07-02    
Medline Journal Info:
Nlm Unique ID:  9301980     Medline TA:  Eur Spine J     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1311-5     Citation Subset:  IM    
Department of Interventional Radiology, Qingdao Municipal Hospital, Qingdao, 266000 Shandong, People's Republic of China.
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MeSH Terms
Intervertebral Disc / pathology*
Low Back Pain / epidemiology,  pathology*
Lumbar Vertebrae / pathology*
Magnetic Resonance Imaging / methods*
Middle Aged
Retrospective Studies
Single-Blind Method

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