| High incidence of reflux esophagitis observed by routine endoscopic examination after gastric pull-up esophagectomy. | |
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MedLine Citation:
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PMID: 12715227 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A gastric tube has been widely used for reconstruction of the esophagus after esophagectomy for esophageal cancer. Reflux esophagitis after esophagectomy is frequently observed. Therefore we retrospectively investigated the risk factors for reflux esophagitis after gastric pull-up esophagectomy in 74 outpatients with thoracic esophageal cancer. Reflux esophagitis was diagnosed endoscopically. Esophagitis was classified according to the Los Angeles classification. Reflux symptoms, medications, and the surgical procedure were reviewed. The relation between reflux symptoms and reflux esophagitis and the influence of the anastomotic site were evaluated. Reflux esophagitis was observed in 53 patients. Severe esophagitis (grade C or D) was found in 75.6% of these patients. Although all patients with esophagitis took antacid agents, histamine receptor-2 blocker was effective in only 35% of them. The correlation between reflux symptoms and reflux esophagitis was not significant. Reflux esophagitis was present in 56.4% of patients with neck anastomosis and in 88.6% of patients with intrathoracic anastomosis ( p = 0.0039). We concluded that routine endoscopic examination is necessary after gastric pull-up esophagectomy because reflux esophagitis is not diagnosed based on reflux symptoms. When a gastric tube is used for reconstruction after esophagectomy, neck anastomosis is recommended to lower the risk of reflux esophagitis. |
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Authors:
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Shunsuke Shibuya; Shin Fukudo; Ryuzaburo Shineha; Shukichi Miyazaki; Go Miyata; Koh Sugawara; Takahiro Mori; Shuichi Tanabe; Norio Tonotsuka; Susumu Satomi |
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Publication Detail:
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Type: Journal Article Date: 2003-04-28 |
Journal Detail:
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Title: World journal of surgery Volume: 27 ISSN: 0364-2313 ISO Abbreviation: World J Surg Publication Date: 2003 May |
Date Detail:
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Created Date: 2003-04-25 Completed Date: 2003-09-22 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7704052 Medline TA: World J Surg Country: United States |
Other Details:
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Languages: eng Pagination: 580-3 Citation Subset: IM |
Affiliation:
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Division of Advanced Surgical Science and Technology, Graduate School of Medicine, Tohoku University, 1-1 Seiryou-machi, Aoba-ku, Sendai 980-8574, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Aged, 80 and over Anastomosis, Surgical Esophageal Neoplasms / surgery Esophagectomy / adverse effects* Esophagitis, Peptic / drug therapy, etiology* Esophagoscopy Female Humans Male Middle Aged Reconstructive Surgical Procedures / adverse effects* Retrospective Studies Stomach / transplantation* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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