Document Detail

High heart rate as predictor of essential hypertension: the hyperkinetic state, evidence of prediction of hypertension, and hemodynamic transition to full hypertension.
MedLine Citation:
PMID:  19615489     Owner:  NLM     Status:  MEDLINE    
Although essential hypertension seems to have a strong hereditary component, the triggering mechanism is unclear. It is likely that the central nervous system via autonomic sympathetic overactivation plays a key role in the development of hypertension. High heart rate has proven to be a strong predictor for cardiovascular disease and a predictor of the development of essential hypertension. Because heart rate is highly influenced by many factors such as anxiety and physical activity, it is sometimes difficult to interpret the value of heart rate measurement in individual persons. Whether heart rate itself is a risk factor for development of hypertension or just a marker for sympathetic overactivation is still a matter of debate, but the presence of elevated heart rate in both hyperkinetic and hypertensive subjects makes it an interesting and easy measurable prognostic marker.
Trygve B Tjugen; Arnljot Flaa; Sverre E Kjeldsen
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Progress in cardiovascular diseases     Volume:  52     ISSN:  1873-1740     ISO Abbreviation:  Prog Cardiovasc Dis     Publication Date:    2009 Jul-Aug
Date Detail:
Created Date:  2009-07-20     Completed Date:  2009-08-05     Revised Date:  2013-05-02    
Medline Journal Info:
Nlm Unique ID:  0376442     Medline TA:  Prog Cardiovasc Dis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  20-5     Citation Subset:  AIM; IM    
Department of Cardiology, Oslo University Hospital, Oslo, Norway.
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MeSH Terms
Heart Rate*
Hypertension / etiology,  physiopathology*
Risk Factors
Sympathetic Nervous System
Tachycardia / complications,  physiopathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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