| High-grade carcinoma of the oral cavity. | |
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MedLine Citation:
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PMID: 2466229 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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High-grade carcinoma of the oral cavity is considered to be an aggressive malignancy associated with a poor prognosis. The tumors are often considered to be relatively radiosensitive. Because previous reviews of oral cavity cancer have contained few patients with grade 4 lesions, little is known about the true behavior of these tumors. Information was collected on 80 patients with high-grade carcinoma of the oral cavity to determine the clinical findings and optimal treatment of this tumor. Primary tumor location, presence of neck metastasis, and clinical stage did not affect survival. Tumor size was a significant risk factor. The 5-year survival rate for patients with high-grade carcinoma treated by combination surgery and radiation (52%) was significantly greater (p less than or equal to 0.05) than that for patients treated by radiation alone (28%) or surgery alone (24%). This study is the first to describe the clinical course of a large number of patients exclusively with high-grade carcinoma of the oral cavity. |
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Authors:
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S F Bansberg; K D Olsen; T A Gaffey |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery Volume: 100 ISSN: 0194-5998 ISO Abbreviation: Otolaryngol Head Neck Surg Publication Date: 1989 Jan |
Date Detail:
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Created Date: 1989-04-20 Completed Date: 1989-04-20 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8508176 Medline TA: Otolaryngol Head Neck Surg Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 41-8 Citation Subset: IM |
Affiliation:
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Department of Otorhinolaryngology, Mayo Clinic, Rochester, MN 55905. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Carcinoma, Squamous Cell* / mortality, pathology, therapy Combined Modality Therapy Epidermis / cytology Female Humans Keratins / analysis Male Middle Aged Mouth Neoplasms* / mortality, pathology, therapy Neoplasm Metastasis / pathology |
| Chemical | |
Reg. No./Substance:
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68238-35-7/Keratins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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